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Determinan Sosial Pasien Tuberkulosis Sebagai Faktor Resiko Penularan Tuberkulosis Riwayat Kontak Serumah di Wilayah Kerja Puskesmas Panjang dan Sukaraja Annas Fadhillah Bilqishti; Dyah Wulan Sumekar; T.A. Larasati
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.22

Abstract

Pulmonary tuberculosis (TB) is transmitted through droplets. The possibility of TB infection is greater in groups close to patient, especially at home. Risk factors that influence TB are social determinants in the form of education level, employment, income and social class; The purpose of this study was to determine the effect of social determinants as risk factors for pulmonary TB transmission with a history of household contact. This research uses Case Control method. Case population was taken from smear TB patients (+) in July-December. Case and control samples were taken by respondents amounted of 30 people. Data analysis was performed by Chi Square test. Results The proportion of respondents from the case sample (53%) was male. For the control sample it was found (76%) that was also male. There was no relationship between education and household contact with TB (P = 0.605) work (P = 0.605), income ((P = 0.193), nor social class (0.111). Risk factors for household contact TB: Social determinants are not a risk factor for transmission of household contact tuberculosis
Penatalaksanaan Penyakit Paru Obstruktif Kronik (PPOK) dengan Hipertensi Melalui Pendekatan Kedokteran Keluarga Lisa Ayu Pratiwi1, TA Larasati2 Lisa Ayu Pratiwi; T.A. Larasati
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.34

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is still a major problem in public health in the world and in Indonesia. In the development of the disease, COPD can be accompanied by hypertension either due to exposure to COPD risk factors or to go hand in hand as a comorbid disease. COPD and hypertension are problems so pay attention to the patient in the management of the disease. Application of Evidence Base Medicine based services to these patients to identify risk factors in the form of lifestyle and clinical problems as well as patient centered management and family approach. This study uses primary data directly from patients and secondary data obtained from patient medical records. The assessment in this case is based on a holistic diagnosis from the beginning, process, and end of the study in a qualitative and quantitative manner. 56-year-old patient with male sex comes with complaints, cough with phlegm Accompanied by shortness of breath lost arise, since 5 days ago. On physical examination obtained blood pressure 160 / 90mmhg breathing frequency 24 times per minute. In the thoracic region examination there is a Barrel Chest, widening of the rib cage, normal vesicular, positive rhonchi, negative wheezing. Internal factors in the form of age 56 years male gender lack of knowledge about COPD disease and hypertension, the purpose of treatment and the prognosis of the disease suffered. . External factors lack understanding about patient disease, lack of awareness of family members not to smoke in the house and cook with a stove. Then the patient and family intervene about the causes, risk factors, clinical symptoms, prognosis, and prevention of recurrence that can be done. So in the evaluation we found the patient had shown improvement with indicators using a questionnaire.
Effect of Vitamins B1, B6, and B12 Supplements on Work Fatigue in Shift Workers at Oil Packing Factory Josua Tumpal Haloman; Rasmi Zakiah Oktarlina; T.A. Larasati
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.239

Abstract

Kelelahan kerja merupakan keluhan yang sering dijumpai pada pekerja, terutama pada pekerja shift. Kondisi fisik dan mental pekerja yang mengalami kelelahan berdampak negatif kepada pekerja itu sendiri dan hasil pekerjannya. Kombinasi multivitamin dengan kandungan vitamin B efektif mengatasi kelelahan fisik dan memperbaiki mood serta kemampuan kognitif. Penelitian ini bertujuan untuk mengetahui pengaruh suplemen multivitamin B1, B6, dan B12 terhadap kelelahan kerja khususnya pada pekerja shift. Penelitian ini merupakan penelitian eksperimental semu dengan sampel sebesar 31 orang pekerja shift di pabrik pengemasan minyak goreng yang sesuai dengan kriteria restriksi. Seluruh subjek diukur kelelahan kerjanya sebelum dan sesudah suplementasi dengan tablet kombinasi vitamin B1, B6 dan B12 selama 7 hari. Kelelahan kerja diukur dengan kuisioner Chalder Fatigue Scale (CFS) dan reaction timer. Data yang diperoleh dianalisis dengan uji statistik untuk melihat perbedaan nilai tengah sebelum dan sesudah suplementasi. Rata- rata skor kuisioner CFS sebelum dan sesudah suplementasi adalah 12,13 dan 8,52. Terdapat penurunan rata- rata skor kuisioner CFS sesudah suplementasi (p=0,001). Rata- rata waktu reaksi sebelum dan sesudah suplementasi adalah 209,45 dan 193,67. Terdapat penurunan rata-rata waktu reaksi sesudah suplementasi (p=0.028). Terdapat pengaruh suplementasi multivitamin B1, B6 dan B12 terhadap kelelahan kerja.
Pengaruh Paparan Asap Rokok Terhadap Koklea Tikus Putih (Rattus norvegicus) Jantan Galur Sprague dawley Evi Kurniawaty; T.A. Larasati; Mira Kurnia
Jurnal Kedokteran Universitas Lampung Vol 3, No 1 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i1.2211

Abstract

Rokok dapat menyebabkan berbagai macam kerusakan organ termasuk koklea sebagai organ pendengaran. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh paparan asap rokok terhadap kerusakan koklea tikus putih (Rattus norvegicus) jantan galur Sprague dawley secara histopatologis. Penelitian ini merupakan penelitian eksperimental laboratorik dengan desain pos ttest only control group design dengan menggunakan 18 ekor tikus putih galur Sprague dawley yang dibagi ke dalam 2 kelompok dan diberi perlakuan selama 14 hari. K1 diberi makan minum biasa, K2 dipapar asap rokok 3 batang/hari selama 14 hari, Hasil kerusakan koklea pada terdapat kerusakan sebanyak K1: 27%; K2: 80%; setiap 9 preparat mikroskopis Data diuji dengan Uji Kolmogorov-Smirnov, didapatkan p=0,037 (p<α) sehingga dapat disimpulkan bahwa terdapat pengaruh paparan asap rokok terhadap koklea tikus putih (Rattus norvegicus) jantan galur Sprague dawley secara histopatologis. Kata kunci: histopatologi, koklea, rokok