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Dedianto Hidajat
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Mikrobioma Kulit dan Peran Probiotik Pada Dermatitis Atopik Sonya Ananda Ellya John; Muhammad fahmi Tamami; Dedianto Hidajat
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.519

Abstract

Abstract Atopic dermatitis (AD) is a multifactorial inflammatory skin disease that has a high prevalence globally. Many underlying factors can be the occurrence of AD, one of which is an imbalance in the composition and diversity of the microbiome in the skin and gut or it can be called a condition of dysbiosis. Management and prevention of dysbiosis can be a treatment strategy in AD. Various studies have been conducted to see the effectiveness of using biotic products, such as probiotics, in the management strategy of AD. Based on available scientific evidence, this review discusses skin microbiome and the role of probiotics in AD. Keywords: atopic dermatitis, dysbiosis, microbiome, probiotic 1Medical Doctor Profession Education Program Faculty of Medicine University of Mataram 2Dermatovenereology Department, Faculty of Medicine University of Mataram / West Nusa Tenggara General Provincial Hospital Email : sonyaaej@gmail.com
Skabies dengan Infeksi Sekunder Pada Sindrom Down Mitha Yunda Pertiwi; Dedianto Hidajat
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.625

Abstract

Scabies is a skin disease caused by Sarcoptes scabiei. The signs and symptoms of scabies such as pruritus and skin lesions in the form of small papules with canaliculus and escoriations. If it’s not treated, complications may occur. The most common complication is secondary infection. The principles in the management of scabies are eradicating mites with pharmacological therapy, preventing the spread of scabies, and overcoming complications. A 1-year-7-month-old child with down syndrome was consulted to the dermatovenereology clinic of RSUDP NTB with complaints of lesion since 1 month ago in the buttocks, genital, between the toes and soles, between the fingers and palms, and around the chest. The patient scratches the spots at night. The patient’s father, mother and brother experiencing similar complaints. Localized status of skin lesions are on the buttocks, external genitalia, thorax, between the fingers and toes, as well as the palms of the hands and feet. The description of lesions were papules with grayish white canaliculus, well-defined, lenticular shape, multiple, discrete arrangement, and regional distribution with scales. In addition, there are white pustules, well-defined, miliary shape, multiple, discrete arrangement, and regional distribution with crusts. The diagnosis of this patient was clinical scabies with secondary infection. The patient was given causative, symptomatic and secondary infection therapy. In addition, to treat patients, the family approach has an important role in eradicating scabies.
PIROXICAM YANG DIDUGA SEBAGAI AGEN PENYEBAB STEVEN-JOHNSON SYNDROME : SEBUAH LAPORAN KASUS Rifqie Courie; Dedianto Hidajat
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.627

Abstract

Steven-Johnson Syndrome (SJS) is an acute mucocutaneous reaction characterized by extensive necrosis and exfoliation of the epidermal layer. The most common etiology or trigger in SJS cases is drugs or their metabolites, followed by infection and idiopathic. The most common drugs that trigger SJS include sulfonamides, non-steroidal anti-inflammatory drugs (NSAIDs) such as oxicam derivatives, imidazole antifungals, cephalosporins, anticonvulsants, allopurinol, broad-spectrum bactericidal agents, and the regimen. Highly Active Anti Retroviral Therapy (HAART). A 42-year- old woman with complaints of blisters on the lips and eyelids and red spots on the body, hands and feet. These complaints began to arise after the patient took the drug Piroxicam. The lesions on the forehead, eyelids, lips and neck in the form of erythematous macular-patch lesions, irregular in shape, poorly demarcated, with lenticular-plaque size, discrete-confulnous arrangement, regional distribution accompanied by erosions and hemorrhagic crusts. lesions on the abdomen, hands and feet in the form of macules – erythematous patches with purpura in the central part, round andin shape irregular, with miliary-plaque size, with discrete-confluent arrangement and generalized distribution with blackish brown erosions and crusts on the left upper quadrants of the abdomen, erosions and hemorrhagic crusts on the left upper arm. The patient was diagnosed with Steven- Johnson Syndrome who later died from aspiration on day 9. The presence of precipitating factors and skin and mucosal lesions that lead to SJS can speed up clinical decision making so that treatment is given more quickly.
Pengaruh Intensitas Pruritus terhadap Kualitas Hidup Pasien Psoriasis Vulgaris di RSUD Provinsi NTB Ayu Niti Wedayani Anak Agung; Dedianto Hidajat
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.800

Abstract

Latar Belakang: Psoriasis merupakan penyakit sistemik berupa inflamasi kronis pada kulit dengan karakteristik berupa plak merah yang berbatas tegas dengan adanya skuama tebal sebagai hasil proses dari gangguan proliferasi dan diferensiasi lapisan epidermis. Psoriasis tidak mengancam jiwa, namun dapat mempengaruhi kualitas hidup pasien Tujuan: Penelitian ini bertujuan ntuk mengetahui adanya hubungan dampak intensitas pruritus terhadap kualitas hidup pasien psoriasis di Kota Mataram. Metode: Penelitian ini merupakan studi potong lintang untuk mengetahui pengaruh intensitas pruritus terhadap kualitas hidup pasien psoriasis pada periode 2019-2020. Data pasien psoriasis diperoleh dari RSUD Provinsi NTB. Intensitas pruritus diukur dengan VAS dan 5D. Kualitas hidup dinilai menggunakan DLQI. Hasil: Ada hubungan yang signifikan antara intensitas pruritus dengan kualitas hidup pasien psoriasis yang dapat dilihat dari nilai P=0.006<0.05. Berdasarkan intensitas pruritus didapatkan derajat keparahan VAS kategori sedang yaitu 29 responden (42.6%) dan 5D kategori moderate yaitu 36(52.9%), serta kualitas hidup terpengaruh sedang pada 28 responden (41.2%). Kesimpulan: Berdasarkan hasil penelitian, didapatkan adanya hubungan antara intesitas pruritus dengan kualitas hidup pasien psoriasis di Kota Mataram. Berdasarkan karakteristik VAS dan 5D didapatkan intensitas purirtus yang sedang, diikuti dengan sebagian besar pasien psoriasis vulgaris memiliki kualitas yang berpengaruh sedang (moderate effect) terhadap kehidupan pasien
Co-Authors Anak Agung Ayu Niti Wedayani Mitha Yunda Pertiwi Muhammad fahmi Tamami Rifqie Courie Sonya Ananda Ellya John