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All Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Makara Journal of Health Research
Wibawa, Awaludin
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Dentistry

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Biokompatibilitas Material Titanium Implan Gigi Fitriani, Cut Yulian; Wibawa, Awaludin
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 8, No 2 (2019)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/10.18196/di.8208

Abstract

Titanium merupakan bahan material yang sudah umum digunakan dalam kedokteran gigi, contohnya sebagai kawat dan implan gigi. Implan gigi sudah banyak digunakan tidak hanya untuk kebutuhan penggantian gigi yang hilang, akan tetapi juga banyak digunakan untuk mendukung rekonstruksi kraniofasial dan untuk kebutuhan perawatan ortodonsi. Pemilihan bahan dasar titanium diyakini karena memiliki sifat biokompatibilitas yang baik. Beberapa studi menunjukkan bahwa ketika titanium ditanamkan dalam tulang, jaringan sekitar akan bereaksi terhadap titanium pada tahap awal, dan kekuatan ikatan tulangnya besar. Pemasangan implan gigi berbahan dasar titanium mengaktivasi sistem imun yang menimbulkan reaksi antara host dan bahan biomaterial. Pada proses osseointegrasi terjadi identifikasi dari badan asing titanium oleh sistem imun dan berkembangnya lingkungan yang mendukung proses pembentukan tulang. Hingga saat ini titanium dipercaya masih efektif digunakan sebagai bahan dasar implan gigi.
Low-Level Laser Therapy to the Major Salivary Glands Increases Salivary Flow and MUC5B Protein Secretion in Diabetic Patients with Hyposalivation: A Preliminary Study Wibawa, Awaludin; Sucharitakul, Jeerus; Dansirikul, Rungthip; Pisarnturakit, Pagaporn P; Bhuridej, Patita; Arirachakaran, Pratanporn
Makara Journal of Health Research Vol. 22, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: To investigate the effect of low-level laser therapy to salivary gland function in diabetic patients with hyposalivation. Methods: Twelve diabetic patients were recruited. A 940-nm indium-gallium-arsenide-phosphide low-power semiconductor diode laser was used to stimulate the major salivary glands with an irradiation time of 40 s; this was done three times a week for 2 consecutive weeks. Patients were given questionnaires related to dry mouth symptoms. Salivary flow rates, questionnaire responses as well as MUC7, MUC5B and histatin 5 protein salivary concentrations were assessed at the first and sixth visits after laser therapy as well at the 6-week follow-up visit. Results: The unstimulated salivary flow rate and MUC5B concentration at the follow-up visit significantly increased (p < 0.01). Histatin 5 concentration significantly decreased at the follow-up visit compared with that at the first visit (p < 0.05). The mean dry mouth score revealed a significant decrease in dry mouth symptoms at the sixth visit and follow-up visit compared with those at the first visit (p < 0.001). The positive correlation between dry mouth score and flow rate was the strongest at the sixth visit (rs = 0.549). Conclusions: Low-level laser therapy increased the salivary flow rate and decreased dry mouth symptoms in diabetic patients.
Co-Authors Arirachakaran, Pratanporn Bhuridej, Patita Dansirikul, Rungthip Fitriani, Cut Yulian Pisarnturakit, Pagaporn P Sucharitakul, Jeerus