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All Journal Indonesian Journal of Medicine Jurnal Sehat Indonesia (JUSINDO)
Meilus, Budi Patria
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Association between Myeloperoxidase and High Sensitive Troponin I on Myocardial Contractility in Acute Myocardial Infarction Patients Wasyanto, Trisulo; Meilus, Budi Patria; Yasa, Ahmad
Indonesian Journal of Medicine Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.014 KB)

Abstract

Background: Myeloperoxidase (MPO) levels have been shown to have prognostic values for death events in acute myocardial infarction (AMI) patients. Increased levels of high sensitive troponin I (hs Trop I) are associated with poorer prognosis in AMI patients. This study aimed to determine the association between levels of MPO and hs troponin I at admisson on myocardial contractility in AMI patients.Subjects and Method: This was a prospective observational analytic study, conducted at Dr. Moewardi General Hospital, Surakarta, from November1, 2018 to January 31, 2019. The study subjects were patients who were diagnosed with AMI. A total of 23 patients were included in this study; 15 patients with ST elevation myocardial infarction (STEMI) and 8 with non ST elevation myocardial infarction (NSTEMI). The dependent variable was myocardial contractility. The inde­pendent variables were MPO and hs Trop I. Blood tests for MPO and hs Trop I was measured at admission and the left ventricular ejection fraction (LVEF) was measured when predis­charge by the Simpson method to examine myo­cardial contractility. The data were analyzed by Pearson correlation run on SPSS 22.  Results: hs Trop I (r= -0.53; p= 0.009) and MPO (r= -0.15; p=0.487) decreased LVEF.Conclusion: Hs Trop I at admission has a correlation with myocardial contractility, and no correlation of MPO at admission with myocardial contractility in AMI patients.Keywords: Myeloperoxidase, High sensitive Troponin I, Acute myocardial infarctionCorrespondence: Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Uni­ver­sitas Sebelas Maret/ Dr. Moewardi Hospital. Jl. Kol. Sutarto 132, Surakarta 57126, Central Java, Indonesia. Email: trisulo.wasyanto@gmail.com.Indonesian Journal of Medicine (2020), 05(04): 265-271https://doi.org/10.26911/theijmed.2020.05.04.01.  
Heart Failure Caused by Incidentally Discovered Right Atrial Myxoma: A Rare Case Report Atikah, Rahmatulhusna; Meilus, Budi Patria
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.248

Abstract

Primary cardiac tumors, though uncommon, play a significant role in medical practice. Cardiac myxoma is the most common benign cardiac tumor, characterized by varying symptoms depending on the location and size of the tumor. We report the case of a 44-year-old woman with complaints of shortness of breath, upper abdominal pain, and leg oedema. Right atrial myxoma was incidentally found after an echocardiography examination, which is an essential tool for detecting and diagnosing cardiac tumors. The patient exhibited clinical improvement with inotropic therapy and antibiotics and was referred for surgical removal of the tumor. Cardiac myxoma surgical procedures generally have a favorable prognosis with a high survival rate. However, postoperative complications such as arrhythmias and infections require close monitoring. Thus, early diagnosis and appropriate management are essential in addressing cardiac myxoma.
Heart Failure Caused by Incidentally Discovered Right Atrial Myxoma: A Rare Case Report Atikah, Rahmatulhusna; Meilus, Budi Patria
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.248

Abstract

Primary cardiac tumors, though uncommon, play a significant role in medical practice. Cardiac myxoma is the most common benign cardiac tumor, characterized by varying symptoms depending on the location and size of the tumor. We report the case of a 44-year-old woman with complaints of shortness of breath, upper abdominal pain, and leg oedema. Right atrial myxoma was incidentally found after an echocardiography examination, which is an essential tool for detecting and diagnosing cardiac tumors. The patient exhibited clinical improvement with inotropic therapy and antibiotics and was referred for surgical removal of the tumor. Cardiac myxoma surgical procedures generally have a favorable prognosis with a high survival rate. However, postoperative complications such as arrhythmias and infections require close monitoring. Thus, early diagnosis and appropriate management are essential in addressing cardiac myxoma.
Co-Authors Ahmad Yasa, Ahmad Atikah, Rahmatulhusna Wasyanto, Trisulo