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The importance of gut health in early life for long term health Kadim, Muzal; Masita, Bertri Maulidya
World Nutrition Journal Vol. 5 No. S2 (2022): Special Issue : critical aspects of early life nutrition, gut health, and deve
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.S2.0001

Abstract

Introduction. The gut microbiota plays an important role in the normal functioning of the host organism. The microbiota of healthy newborn affected by many factors such as prenatal exposures, maternal nutrition, mode of delivery, type of feeding, introduction to solid food and its type, geography, and antibiotics consumption; and its composition continues to mature until reaching 3 years of age. Normal gut microbiota is essential in gut health, and play an important role in our homeostasis. Therefore, gut microbiota is considered a crucial factor for proper early life development and lifelong health. Prebiotics, along with probiotics, may alter gut microbiota composition thus play a role in the prevention of various diseases associated with dysbiosis condition. Methods. Advanced search for relevant literatures in PubMed, Cochrane, and Willey was conducted. After assessing the relevancy and eligibility, articles were selected and critically appraised. Conclusions. Accumulating evidence from different studies has shown that the occurrence of a disease is often preceded by early alterations of the microbiota. Many studies established correlation between gut microbiota dysbiosis with diseases pathogenesis i.e obesity and other metabolic syndrome, asthma and allergies, also stress-related disorder. Prebiotic supplementation has proven to be effective in obesity, asthma and allergies management, also beneficial for immune system.
FACTORS ASSOCIATED WITH LOWER BIRTH WEIGHT AMONG INFANTS IN SOUTH KALIMANTAN PROVINCE, INDONESIA Winarno, Nibras Azeenshia; Pujonarti, Siti Arifah; Triyanti, Triyanti; Irawati, Anies; Perkasa, Al Ilham Ksatria Gagah; Sundjaya, Tonny; Masita, Bertri Maulidya
Journal of Indonesian Specialized Nutrition Vol. 4 No. 1 (2026): Journal of Indonesian Specialized Nutrition
Publisher : PT. Varians Statistik Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v4i1.70

Abstract

Background: According to the thrifty phenotype hypothesis, individuals who have a Birth Weight less than 3000 grams are at risk of suffering from metabolic syndrome and type 2 diabetes mellitus in adulthood. The prevalence of Diabetes Mellitus and metabolic syndrome in Indonesia and South Kalimantan is increasing. In 2023, the Indonesian Health Survey (Survey Kesehatan Indonesia /SKI) data showed that the percentage of Birth Weight less than 3000 grams in Indonesia reached 35.3% and in South Kalimantan 41.7%. This indicates an increase in the percentage of Birth Weight less than 3000 grams in South Kalimantan when compared to the 2018 Riskesdas data, the percentage of BW less than 3000 grams in South Kalimantan was 37.5%. This is a quantitative study using a cross-sectional research design and using secondary data from the SKI 2023. Data were analyzed univariately and bivariately with complex samples and chi square tests. The results of the study found a significant association between Birth Weight and Chronic Energy Deficiency (p-value = 0.001) where mothers with a history of Chronic Energy Deficiency had a 5 times higher risk. Conclusion: History of Chronic Energy Deficiency among mothers is an important determinant of infants’ Birth Weight in South Kalimantan. Further, these findings might contribute to the prevention strategy of Non-Communicable Diseases in South Kalimantan.