Rahmawati, Vita Kusuma
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THE CORRELATION OF CARDIOMEGALY AND STROKE SEVERITY: AN ANALYTICAL STUDY Awwalia, Fildza; Rahmawati, Vita Kusuma
Journal of Pain, Headache and Vertigo Vol. 7 No. 1 (2026): March
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Stroke is characterized as a neurological deficit attributed to an acute injury of Central Nervous System (CNS) by a vascular cause. Cardiomegaly means enlargement of heart. Both stroke and cardiomegaly are related to vascular problems, but the correlation between them remains unclear. Objective: This study was conducted to examine risk factors related to stroke severity (based on National Institute of Health Stroke Scale) especially cardiomegaly at Lumajang Islamic Hospital in January to June 2025. Method: This study is an analytic observational study, retrospective data by using hospital medical records. Data were obtained from 124 inpatients cases admitted between January to June 2025 in Lumajang Islamic Hospital. The risk factors were studied are cardiomegaly, hypertension, diabetes mellitus, age, time of patient arrival. Results: The Pearson Chi-Square test indicated no significant correlation between cardiomegaly and NIHSS (stroke severity) with p = 0,080, nor with hypertension (p = 0,621), diabetes mellitus (p = 0,345) or age (p = 0,721). A statistically significant correlation was observed between the patient's arrival time and the severity of stroke (p = 0.000), including the arrival time of patients with cardiomegaly at the hospital (p = 0.020). Conclusion: This study demonstrated no significant correlation between cardiomegaly, hypertension, diabetes or age to stroke severity. However, significant correlation was found in patients arrival time including in cardiomegaly patients. These findings highlight the critical importance of early detection and timely medical intervention in stroke cases, particularly for patients with cardiomegaly.
The Impact of Elevated Mean Arterial Pressure on Mortality in Spontaneous Subarachnoid Hemorrhage Sani, Achmad Firdaus; Laisari, Taurus; Yahya, Muh. Wildan; Rahmawati, Vita Kusuma; Hamdani, Faishol; Kurniawan, Dedy; Setyowatie, Sita
Journal of Neurointervention and Stroke Vol. 1 No. 1: MAY 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.11.2

Abstract

Highlight: Elevated MAP is associated with increased in-hospital mortality in SAH patients High MAP increases the risk of rebleeding, cerebral edema, and vasospasm MAP, age, infection, and hydrocephalus are independent predictors of mortality ABSTRACT Introduction: Subarachnoid hemorrhage (SAH) remains a critical neurological emergency with high mortality and morbidity. Mean arterial pressure (MAP) plays an importance role in cerebral perfusion and hemodynamic stability in SAH patients. However, excessive MAP elevation potentially worsening clinical outcomes. This study investigates the impact of elevated MAP on in-hospital mortality among SAH patients. Objective: This study investigates the impact of elevated MAP on in-hospital mortality among SAH patients.  Method: A retrospective cross-sectional study was conducted using medical records of SAH patients admitted to Dr. Soetomo Academic Medical Center Hospital from 2013 to 2021. A total of 360 patients met the inclusion criteria. MAP was calculated upon admission and categorized as ≥125 mmHg or <125 mmHg. The primary outcome was in-hospital mortality. Logistic regression analysis was performed to assess the association between MAP and mortality while adjusting for confounders. Result: Among 360 SAH patients, 44.8% did not survive hospitalization. The mean age was 54 years, with an initial mean MAP of 117.45±21.6 mmHg. Bivariate analysis showed that MAP ≥125 mmHg significantly increased mortality risk (OR = 1.93; 95% CI: 1.24–2.98; p = 0.002). Multivariate logistic regression identified MAP ≥125 mmHg as an independent predictor of mortality (Adjusted OR = 1.795; p = 0.012), alongside age (Adjusted OR = 2.043; p = 0.004), infection (Adjusted OR = 2.442; p = 0.001), and hydrocephalus (Adjusted OR = 2.174; p = 0.003). Conclusion: Elevated MAP (≥125 mmHg) is significantly associated with increased in-hospital mortality in SAH patients. These findings highlight the importance of early hemodynamic management in SAH to improve patient survival.
Deferring Angioplasty and Stenting based on Natural Progression in Severe Middle Cerebral Artery Stenosis: An Observation of Two Cases Rahmawati, Vita Kusuma; Sani, Achmad Firdaus; Kurniawan, Dedy; Yahya, Muh. Wildan; Hamdani, Faishol
Journal of Neurointervention and Stroke Vol. 1 No. 1: MAY 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.11.5

Abstract

Highlight: MCA stenosis may remodel spontaneously or progress to complete occlusion Serial imaging observing progression spots high-risk cases, guiding intervention ABSTRACT Introduction: Severe middle cerebral artery (MCA) stenosis, as one of the intracranial atherosclerotic diseases, is a major cause of ischemic stroke. The role and optimal timing of interventions, such as angioplasty and stenting, remain subjects of debate, particularly due to the variable natural disease progression. While some cases improve spontaneously, others progress to total occlusion, necessitating comprehensive evaluation of individualized treatment approaches. Cases: This case series presents two patients with severe MCA stenosis, each of whom followed a distinct clinical courses. The first patient had 88% stenosis in the M1 segment of the right MCA (NIHSS 3, mRS 2), which spontaneously improved to 57% within days (NIHSS 2, mRS 2), with enhanced distal flow, leading to the decision to defer angioplasty and stenting. In contrast, the second patient initially had severe left MCA stenosis (NIHSS 10, mRS 4), which progressed to total occlusion within three months (NIHSS 10, mRS 4), also resulting in deferred intervention. Serial cerebral digital subtraction angiography (DSA) facilitated the observation of vascular evolution and collateral circulation, guiding decisions about intervention. Conclusion: The clinical outcomes of MCA stenosis range widely, from spontaneous resolution to progressive occlusion. Close serial imaging observation of collateral circulation and natural progression is essential for guiding decisions about angioplasty and stenting.