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Perbandingan uji diagnostik GeneXpert MTB/RIF untuk mendeteksi resistensi rifampicin Mycobacterium tuberculosis pada pasien Tb paru di RSUP dr. Moh. Hoesin Palembang Erizka Rivani; Tia Sabrina; Venny Patricia Patricia
JURNAL KEDOKTERAN DAN KESEHATAN Vol 6, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.v6i1.7236

Abstract

Tuberkulosis (TB) masih menjadi masalah global. TB menduduki peringkat kedua penyebab kematian dari seluruh penyakit infeksi di dunia. Kelemahan dalam mendiagnosis dan pengobatan cepat selain dapat berdampak pada pasien, juga terhadap perkembangan resistensi sekunder dan penyebaran dari penyakit ini. Sebagai alternatif, teknik molekuler diagnostik dapat mempercepat TAT dan meningkatkan sensitifitas dan spesifisitas. Tes GeneXpert MTB/RIF merupakan mesin otomatis dengan penggunaan mudah dan cepat yang menggunakan prinsip nested real-time PCR dan teknologi molekuler untuk mendeteksi M. tuberculosis (MTB) dan resistensi obat rifampicin (RIF). Penelitian ini merupakan studi observasional analitik di laboratorium dengan pendekatan purposive sampling. Penilaian hasilĀ  sensitivitas dan spesifisitas GE memiliki nilai 97% dan 93% terhadap mikroskopis BTA; Sensitivitas dan spesifisitas GE memiliki nilai 97% dan 62% terhadap kultur MTBC; Persentase deteksi Rifampisin resisten pada GE sebesar 167(31%) lebih tinggi dari pada kultur MTBC sebesar 103(21.7%); Ada 3 sampel dari 5 sampel yang hasil BTA positif dan GE negatif yang memiliki gen hsp65 yang menunjukkan adanya bakteri MOTT
Education on Disease Risk Factors in Adapting New Habits to Prospective Hajj Pilgrims at KBHI Bisri-Pusri Palembang City Emma, Emma Novita; Agita Diora Fitri; Tia Sabrina; Andyra Priandhana; Muhammad Musa; M.Taufik Wijaya
International Journal Of Community Service Vol. 1 No. 2 (2021): August 2021 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i2.18

Abstract

Health istitha'ah is the health ability of the pilgrims physically and mentally with a measurable health assesment. It is essential for every citizen who will perform the hajj pilgrimage. The Indonesian Ministry of Health through the Non-Infectious Disease Integrated Service Post (Posbindu PTM) implements an early detection and prevention program for non-infectious diseases in sub-districts, schools or colleges, institutions or workplaces, and Hajj guidance groups (KBIH) especially for pilgrims. The department of public health and community medicine (IKM-IKK) of the Faculty of Medicine, Sriwijaya University perform an education on the detection of risk factors for non-infectious diseases and physical fitness assesment of prospective pilgrims in the context of community service activities at KBIH Bisri Palembang. Examinations were done on 40 prospective pilgrims using the Rockport test method. The results of the examination showed that the 24 pilgrims had moderate fitness level (60%). The blood pressure test results showed that 9 pilgrims had hypertension (22%) and the nutritional status test showed that 20 pilgrims were overweight and obese (38.5%). In addition, there is an assesment for prospective hajj pilgrims in order to understanding risk factors for non-infectious diseases. The result shows that there is a significant increase in understanding about non-infectious diseases in the adaptation of new habits.