Article Per Year (5 Year)
p-Index From 2020 - 2025
0.702
P-Index
This Author published in this journals
All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan SCRIPTA SCORE Scientific Medical Journal Cermin Dunia Kedokteran
Mahendra, Cipta
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Cermin Dunia Kedokteran

 1 
Terapi CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats): Pengenalan untuk Penggunaan Klinis Mahendra, Cipta
Cermin Dunia Kedokteran Vol 48, No 11 (2021): Kardio-SerebroVaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.135 KB) | DOI: 10.55175/cdk.v48i11.1560

Abstract

CRISPR(Clustered Regularly Interspaced Short Palindromic Repeats) mulai mendapat perhatian saat Jennifer Doudna dan Emmanuelle Charpentier mendapat hadiah Nobel bidang Kimia tahun 2020 lalu. Meskipun relatif merupakan terobosan baru, terapi CRISPR memiliki potensi besar di bidang medis. Tinjauan ini merupakan pengantar untuk mengenal dan memahami CRISPR sebagai sebuah upaya terapi alternatif di masa depan. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) starts to gain attention when Jennifer Doudna and Emmanuelle Charpentier were awarded Nobel Prize in Chemistry in 2020. CRISPR is relatively a new discovery in science, but it has a great potential in medicine. This review is to give an overview on CRISPR as a promising medical therapy.
Peutz-Jeghers Syndrome Mahendra, Cipta
Cermin Dunia Kedokteran Vol 48, No 12 (2021): General Medicine
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.303 KB) | DOI: 10.55175/cdk.v48i12.1574

Abstract

Sindrom Peutz-Jeghers (Peutz-Jeghers Syndrome/PJS) merupakan penyakit herediter langka dengan ciri klinis pigmentasi mukokutaneus dan polip gastrointestinal. Hingga kini, satu-satunya upaya terapi adalah eliminasi polip melalui metode endoskopi dan/atau operasi laparatomi abdomen invasif. Penderita PJS memiliki risiko tinggi mendapat berbagai jenis kanker sehingga diperlukan skrining rutin. Para penderita PJS perlu mendapat edukasi dan dukungan mental. Diperlukan riset lebih mendalam untuk tatalaksana terbaik sindrom PJS.Peutz-Jeghers Syndrome (PJS) is rare hereditary disease with mucocutaneous pigmentations and gastrointestinal polyps as the most prominent clinical features. The only approved treatment is to eliminate the polyps by endoscopy and/or invasive abdominal laparotomy surgery. Patients with PJS have a high lifetime risk of various cancers and warrants regular surveillance for early signs of malignancies. PJS patients need to be well-informed and supported by the treating physicians to cope with their PJS status. More research in the management of PJS is needed.
Co-Authors