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All Journal Journal of Islamic Medicine Jurnal Rekonstruksi dan Estetik
Malelak, Elric Brahm
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Medicine & Pharmacology

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TREATMENT OF PRESSURE ULCERS OF THE SCALP IN DECOMPENSATED HYDROCEPHALY: A CLINICAL CHALLENGE. Kale, Letitia Bellavesta; Malelak, Elric Brahm; Datusanantyo, Robertus Arian; Ullah, Wajahat; Ali, Ahmed Mohamed Ahmed; Thumar, Dhyey; Kumar, Kundan
Jurnal Rekonstruksi dan Estetik Vol. 8 No. 2 (2023): Jurnal Rekonstruksi dan Estetik, December 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v8i2.49972

Abstract

Highlights: Studies of pressure injury in hydrocephalus patients are very limited. To determine the staging and diagnosis, clinicians must consider the anatomical location of pressure injury, especially in children. Pressure injury increases the risk of shunt infection in hydrocephalus patients. Abstract: Introduction:  A pressure injury is ‘localized injury to the skin and/or underlying tissue usually over a bony prominence, that caused by compression. Multiple studies have demonstrated that age, moisture, immobility, and friction/shear are key risk factors. We report a challenging case of multiple pressure injury over the scalp in hydrocephalus patients. Case Illustration: Three toddlers with Hydrocephalus was consulted due to multiple Pressure Injury over the scalp in the bilateral temporo-parietal and occipital region. After ventriculo-peritoneal shunting (VP-shunt), the wounds were managed in accordance with TIMERS guidelines. Discussion: Pediatric tissues are more susceptible to deformation injuries. Severe skull deformity and macrocephaly are serious problems that may lead to difficulties in head control and child positioning increases the risk of pressure injury. After VP-shunt, wound care is even more challenging since the surgical wound is closely related to pressure injuries. Shunt exposure can be occurred on these patients. According to both examination and intervention of TIMERS guidelines are essential as well as controlling risk factors of pressure injury development.     Conclusion: Surgeons should be aware that children with hydrocephalus may experience scalp injuries and changes to their body composition, which challenge the diagnosis and care process.
Penetapan Kadar Senyawa Epikatekin dalam Ekstrak Air Kulit Batang Faloak (Sterculia quadrifida R.Br.) Berbagai Varian sebagai Antihepatitis C Dean, Muhajirin; Telussa, Arley Sadra; Malelak, Elric Brahm
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.28895

Abstract

Background: East Nusa Tenggara Province, Indonesia, is a common location for the faloak plant. Due to its epicatechin compounds, the faloak plant (Sterculia quadrifida R.Br) has potential for use as an anti-hepatitis C treatment. Objective: This study aims to identify the highest epicatechin content of faloak obtained from various places, to optimize the cultivation and processing of faloak plants into herbal antihepatitis C medicines. General therapy for hepatitis C causes side effects such as hemolytic anemia, pruritus, asthenia, neutropenia, myalgia, respiratory problems, cardiovascular disorders, and even teratogenic. Methods: Faloak plants obtained from 3 locations (Rote, Timor, and Semau Islands) were extracted with water solvent. The extracts were then analyzed by HPLC to measure epicatechin levels using standard. Results: All three samples from different islands demonstrated the presence of epicatechin, as indicated by their retention times matching the standard compound. The retention times for the Faloak water extracts from Rote, Timor, and Semau Islands were 12.420, 12.427, and 12.353, respectively. The assay results revealed that the sample from Rote Island had the highest concentration, measuring 24.810%. Conclusion: All faloak water extracts contain epicatechin, with the highest concentration found in faloak from Rote Island.
Co-Authors Ali, Ahmed Mohamed Ahmed Datusanantyo, Robertus Arian Kale, Letitia Bellavesta Kumar, Kundan Telussa, Arley Sadra Thumar, Dhyey Ullah, Wajahat