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Sihotang, Hillery
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Education Medicine & Pharmacology Neuroscience Public Health

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Polycystic Kidney Disease Stadium Lanjut dengan Komplikasi Ekstrarenal pada Wanita 55 Tahun : Laporan Kasus Sihotang, Hillery; Sijabat, Hotmen
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1606

Abstract

Polycystic Kidney Disease (PKD) is an inherited kidney disorder characterized by the formation of multiple fluid-filled cysts in the kidneys, frequently involving other organs such as the liver. It is a progressive condition that can lead to end-stage renal disease (ESRD). This case report aims to explore the clinical course and management approach of a PKD patient with poor follow-up adherence since diagnosis. A 55-year-old female with a diagnosis of PKD since 2009 presented with abdominal enlargement, fatigue, and right upper quadrant discomfort. Despite a positive family history, the patient did not receive regular monitoring and relied on herbal remedies. Over 16 years, disease progression was marked by significant increases in serum urea and creatinine, development of multiple renal and hepatic cysts, and progression to chronic kidney disease (CKD) stage 4–5. The patient currently suffers from hepatic cyst complications and ESRD. This case highlights the accelerated progression of PKD in the absence of consistent clinical monitoring and early therapeutic intervention. It underscores the importance of early detection, regular renal function evaluation, patient and family education, and supportive care. Planning for renal replacement therapy and genetic screening of offspring are crucial to mitigate disease progression and improve outcomes in PKD patients.
Co-Authors Hotmen Sijabat