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Gaya hidup penderita diabetes mellitus Tipe 2 pada masyarakat di daerah perkotaan Febriyan, Heironimus Billy
Wellness And Healthy Magazine Vol 2, No 2 (2020): Agustus
Publisher : Universitas Aisyah Pringsewu (UAP) Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/well.022.82000139

Abstract

Diabetes Mellitus Type 2 is a disease characterized by high glucose levels in the blood exceed the standard value. The condition causes the disruption of the function of organs, causing all sorts of problems, among others such as eye disorders, heart, healing wounds, and stroke. Diabetes mellitus type 2 has some risk factors such as gender, age, family history, diabetes, obesity, hypertension, dyslipidemia, less activity, fat and carbohydrate intake high. The residence also can be a risk factor for type 2 diabetes mellitus where urban areas are associated with a change in lifestyle and dietary habits compared with the countryside. It became one of the causes of the increase in type 2 diabetes mellitus in urban areas. Conclusion It was found that type 2 diabetes mellitus is very influential, especially in decreased quality of life, especially in urban areas.
HIPERTENSI PADA DIABETES MELLITUS: SEBUAH TINJAUAN PUSTAKA Febriyan, Heironimus Billy; Utama, Winda Trijayanthi
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1729

Abstract

Hypertension in patients with diabetes mellitus is a significant clinical problem because it increases the risk of cardiovascular and renal complications. The pathophysiology of this condition involves interactions between insulin resistance, activation of the renin–angiotensin–aldosterone system (RAAS), endothelial dysfunction, and oxidative stress, which trigger vasoconstriction, sodium retention, and increased vascular stiffness. Various clinical guidelines, including those of the American Diabetes Association (ADA), set a blood pressure target of <130/80 mmHg to reduce the risk of long-term complications. Evidence from clinical trials such as ABCD shows that intensive blood pressure control provides benefits in terms of the progression of retinopathy, albuminuria, and stroke risk. This article was compiled using a narrative review approach by examining the latest literature from international journals and clinical guidelines related to hypertension in diabetes. Sources were selected based on relevance, recency, and strength of evidence. The analysis was descriptive to summarize pathophysiology, blood pressure target recommendations, treatment options, and the role of lifestyle changes. Management of hypertension in diabetes requires a combination of pharmacological therapy and lifestyle modifications. ACE inhibitors and ARBs are the first choice due to their renal protective benefits, while calcium antagonists and thiazide diuretics are used as adjunctive therapy. Lifestyle interventions such as salt restriction, increased fruit and vegetable consumption, regular physical activity, weight loss, and alcohol restriction provide moderate blood pressure lowering effects and improve metabolic health. A comprehensive approach encompassing metabolic, pharmacological, and lifestyle management is crucial for reducing morbidity and mortality in patients with diabetes and hypertension.