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All Journal Buletin Farmatera
RAHMAT, SAID MUNAZAR
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Medicine & Pharmacology

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Giving Yali Pear Juice (Pyrus Brettschneider) Is Influential Against Total Cholesterol Levels in the Blood in Patients with Hypercholesterolemia Rizkina, Cut Suhaila; Rahmat, Said Munazar
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.27092

Abstract

Abstract: Hypercholesterolemia is one of the abnormalities that occur in the body's metabolism, which is shown to cause an increase in total cholesterol levels exceeding the normal limit, which is 200 mg/dL. Metabolic disorders can increase blood fat levels due to enzyme deficiencies, LDL receptor abnormalities, and genetic factors that trigger excess cholesterol production or decrease cholesterol clearance by the liver. Natural ingredients of fruit can help reduce body fat levels. Yali pears contain compounds such as carotenoids, chlorophyll, triterpenoids, polyphenols, fibre, and vitamin C that can help improve blood lipid profiles. This study looked at the effect of giving Yali pear juice on total cholesterol levels in the blood, so that it can be one of the natural additional treatments for hypercholesterolemia patients. This study uses a non-equivalent control group design, namely research conducted with a pre- and posttest, which is divided into two groups, namely the treatment group given Yali pear juice and the control group given a placebo. Yali pear juice and a placebo were given for 10 days. Checking total cholesterol levels in the blood using GCU easy touch tools before and after the study. Data analysis using the T-test parametric test.  Analysis of pre-test data with the post-test of the treatment group obtained a result of p0.05, which means that there is an effect of Yali pear juice on total cholesterol levels in the blood. In the pre-test with the post-test, the control group had p0.05, which means there was no placebo effect on total cholesterol levels in the blood. Giving Yali pear juice for 10 days has an effect on reducing total cholesterol levels in the blood.
The Effect of Thesis Writing on Stress Symptoms among Medical Students at UMSU Faculty of Medicine Nursaputra, Dwi Wahyu Budi; Rahmat, Said Munazar
Buletin Farmatera Vol 11, No 3 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i3.28076

Abstract

Introduction: Migraine is a type of primary headache defined as recurrent headache attacks that vary widely in both intensity and duration. One of the risk factors or causes of migraine is stress. Stress is a response to stressors that may threaten a person’s safety and well-being. Stress symptoms are classified into normal and stress-related symptoms. This study aimed to determine the relationship between stress symptoms and the occurrence of migraine among students who are writing their thesis at the Faculty of Medicine, UMSU. Methods: This was an analytical study with a cross-sectional design, in which data were collected at a single point in time. The sample consisted of 81 participants. Data were collected by completing a questionnaire via Google Forms. The sampling technique used was purposive sampling based on predefined inclusion and exclusion criteria, and the data were analyzed using the Chi-square test. Results: The study showed a significant association between stress symptoms and the occurrence of migraine among students who were writing their thesis at the Faculty of Medicine, UMSU, as evidenced by a p-value of 0.00, which is less than 0.05. Conclusion: Based on the results, there is a relationship between stress symptoms and the occurrence of migraine among students writing their thesis at the Faculty of Medicine, UMSU.
Co-Authors Nursaputra, Dwi Wahyu Budi Rizkina, Cut Suhaila