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All Journal Indonesian Journal of Educational Studies Biology, Medicine, & Natural Product Chemistry Journal of Multidisciplinary Science: MIKAILALSYS
OJETUNDE, Ayodeji Oluwatobi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Environmental Science Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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COVID-19 lockdown policy impact on students' psychological, behavioral, and daily routine changes: A case study of Gusau residents in Nigeria OJETUNDE, Ayodeji Oluwatobi; BAMIGBALA, Olateju Alao; OYEGOKE, Toyese
Indonesian Journal of Educational Studies Vol 23, No 2 (2020): Indonesian Journal of Educational Studies
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/ijes.v23i2.18973

Abstract

In the exploration of a better approach to managing education sectors in developing nations during the pandemic era, this study attempts to evaluate the impact of the COVID-19 lockdown policy on students' mental health in Gusau, one of the towns in Nigeria, through the investigation of how the students' psychology, behavior, and routine activities were affected by the introduction of lockdown protocols/policy during the COVID-19 pandemic crisis. The investigation was done using a hybrid method that employs a combination of the descriptive and factorial design method, where 201 students participated in the study. Findings from the study indicated that male students were 2% above female; two-third of the students were under-age; the students' attending private schools were 5% above the ones attending public schools; while two-third of the students were attending lower/middle school. The study confirmed that the students' psychology was significantly affected by the lockdown protocols, likewise their behaviors and routine activities. Some factors contributing to the effects were reported. And recommendations were made to the effect for the government to transform Nigeria states' learning system into being a hybrid learning system that would combine the use of both physical and virtual learning platforms at all levels of education, which would go a long way to manage the behavior, psychology, and routine activities of the students better, both during a pandemic and non-pandemic era
The Neuroprotective and Therapeutic Effects of Medicinal Plants and Natural Products against Aluminium Chloride-Induced Alzheimer's Disease: Recent Update Ojetunde, Ayodeji Oluwatobi
Biology, Medicine, & Natural Product Chemistry Vol 13, No 1 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.131.7-33

Abstract

Alzheimer's disease currently affects more than 35 million individuals worldwide. Aluminium has been implicated in the pathogenesis of various cognitive disorders. Meanwhile, aluminium chloride (AlCl3) has a significant impact on the progression of neurodegenerative diseases including Alzheimer's disease. The majority of Alzheimer's disease medications now on the market are cholinesterase inhibitors. However, the effectiveness of these drugs is limited because they can't totally arrest the progression of the disease. The utilization of medicinal plants and natural products may present excellent prospective options for Alzheimer's disease prevention and therapy. This study summarized medicinal plants and natural products for the prevention and treatment of AlCl3-induced Alzheimer's disease as an alternative therapy using published data in the literature from the years 2021-2023. The medicinal plants and natural products help to reduce Alzheimer's disease pathogenesis by controlling different pathways and could be used as a therapeutic agent against the symptoms. The majority of the medicinal plants and natural products discussed in this review have been shown to have neuroprotective, antioxidant, anti-amyloid, anti-inflammatory, anticholinesterase, anti-apoptotic, and therapeutic actions. Therefore, medicinal plants and natural products may offer neuroprotective and therapeutic effects in the treatment of Alzheimer's disease.
Examining Factors Influencing Antenatal Care Visits in Nigeria Bamigbala, Olateju Alao; Odey, Solomon Etia; Ojetunde, Ayodeji Oluwatobi; Ikrimat, Aliyu; ThankGod, Joshua
Journal of Multidisciplinary Science: MIKAILALSYS Vol 3 No 1 (2025): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v3i1.5266

Abstract

The number of maternal deaths worldwide linked to pregnancy and childbirth is high in Nigeria. Meanwhile, attending the recommended number of antenatal care (ANC) appointments may help reduce maternal morbidity and death. This research sought to examine the factors influencing ANC visits in Nigeria. This study employed secondary data extracted from the Nigeria Demographic and Health Survey 2018. A total sample of 21,427 women was included. Data analysis was carried out using the Zero-Inflated Negative Binomial Regression. The level of significance was p < 0.05. Among the participants, 5,337 (24.9%) did not attend any ANC visits. As the number of visits increases, there is a gradual decrease in frequency, with 4 visits being the most common (12.7%). Findings revealed that place of residence, maternal education, insurance coverage, marital status, partner’s education, region, and age of the mother consistently impacted additional ANC visits. While the place of residence, maternal education, insurance coverage, partner’s education, region, and age of the mother impacted zero ANC visits. Policymakers should focus on rural areas and those with lower education levels to improve ANC visits. Furthermore, specific attention should be given to pregnant women over 18 years of age to ensure they receive adequate ANC.
Nigella Sativa Oil Protects Against Aluminium Chloride-Induced Cognitive Impairment Via Modulation of Cholinergic Activity, Brain Neurotransmitter, and Oxidative Stress Ojetunde, Ayodeji Oluwatobi; Alhassan, Abdulwahab; Suleiman, Ibrahim; Isa, Ahmed Sherif
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.739-746

Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment, with no known cure. This study investigated the potential protective effects of Nigella sativa oil (NSO) on aluminium chloride-induced cognitive impairment in Wistar rats. Twenty-four rats were divided into four groups. Group I received 1 ml/kg of distilled water. Groups II-IV were administered aluminium chloride (100 mg/kg). Groups III and IV were co-treated with NSO at 1 ml/kg and 2 ml/kg, respectively. Neurobehavioral assessments (Morris water maze and Y-maze) were performed, followed by biochemical analysis of brain tissues. Aluminium chloride significantly (p < 0.05) impaired spatial learning and memory and decreased the percentage of alternation. It also significantly (p < 0.05) increased acetylcholinesterase level, glutamate concentration, and malondialdehyde level, and decreased antioxidant markers. Meanwhile, Nigella sativa oil (1 ml/kg and 2 ml/kg) significantly (p < 0.05) improved learning ability and spatial memory, and increased percentage alternation in the Y-maze test. Nigella sativa oil also significantly (p < 0.05) decreases acetylcholinesterase, glutamate, and malondialdehyde, and increases antioxidant biomarkers. This study showed that Nigella sativa oil can improve cognitive and spatial learning functions via modulation of cholinergic activity, brain neurotransmitters, and oxidative stress.
Co-Authors Alhassan, Abdulwahab BAMIGBALA, Olateju Alao Ikrimat, Aliyu Isa, Ahmed Sherif Odey, Solomon Etia OYEGOKE, Toyese Suleiman, Ibrahim ThankGod, Joshua