Ebnudesita, Faiza Rahma
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Pengetahuan Abatisasi dengan Perilaku Penggunaan Abate Ebnudesita, Faiza Rahma; Sulistiawati, Sulistiawati; Prasetyo, R. Heru
HIGEIA (Journal of Public Health Research and Development) Vol 5 No 1 (2021): HIGEIA: January 2020
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/higeia.v5i1.39447

Abstract

ABSTRAK Demam berdarah dengue (DBD) masih menjadi masalah kesehatan global. Indonesia berada pada urutan kedua dengan kasus DBD tertinggi di dunia. Tujuan penelitian ini untuk menganalisis hubungan pengetahuan abatisasi dengan perilaku penggunaan abate di Desa Jatisari, Kabupaten Madiun. Penelitian ini adalah jenis penelitian analitik observasional dengan rancangan studi potong lintang, dilaksanakan pada bulan Maret 2019 – Mei 2020 di Desa Jatisari, Kabupaten Madiun, Jawa Timur. Populasi dan sampel pada penelitian ini dipilih menggunakan metode total sampling, yakni seluruh ibu atau pengambil keputusan dalam rumah tangga dan berumur 20 hingga 65 tahun yang bersedia sebagai responden, didapatkan 60 responden yang memenuhi kriteria inklusi. Data dikumpulkan melalui wawancara menggunakan kuesioner dan diuji menggunakan Spearman. Mayoritas responden memiliki pengetahuan abatisasi yang rendah (46,7%) diikuti dengan perilaku penggunaan abate yang rendah (91,7%). Pengetahuan abatisasi tidak berhubungan signifikan dengan perilaku penggunaan abate, akan tetapi memiliki kecenderungan untuk berhubungan (p= 0,07). ABSTRACT Dengue hemorrhagic fever (DHF) is still a global health problem. Indonesia is the second largest position of DHF in the world. This study aimed to analyze the relationship between knowledge of abatization and abate usage behavior in Jatisari Village, Madiun Regency. This study was an observational analytic with cross-sectional design, was conducted in March 2019 - May 2020 in Jatisari Village, Madiun Regency, East Java. The population and sample in this study were selected using the total sampling method, including all mothers or decision makers in the household aged 20 to 65 willing years to be respondents, with 60 of them fulfilled the inclusion criteria. Data were collected through interviews using a questionnaire and processed by Spearman analysis. Majority of the respondents have a low abatization knowledge (46.7%) followed by low abate usage behavior (91.7%). The level of knowledge of abatization was not significantly related to abate usage behavior, but has a tendency to relate (p = 0.07).
Pengetahuan Abatisasi dengan Perilaku Penggunaan Abate Ebnudesita, Faiza Rahma; Sulistiawati, Sulistiawati; Prasetyo, R. Heru
HIGEIA (Journal of Public Health Research and Development) Vol 5 No 1 (2021): HIGEIA: January 2021
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/higeia.v5i1.39447

Abstract

ABSTRAK Demam berdarah dengue (DBD) masih menjadi masalah kesehatan global. Indonesia berada pada urutan kedua dengan kasus DBD tertinggi di dunia. Tujuan penelitian ini untuk menganalisis hubungan pengetahuan abatisasi dengan perilaku penggunaan abate di Desa Jatisari, Kabupaten Madiun. Penelitian ini adalah jenis penelitian analitik observasional dengan rancangan studi potong lintang, dilaksanakan pada bulan Maret 2019 – Mei 2020 di Desa Jatisari, Kabupaten Madiun, Jawa Timur. Populasi dan sampel pada penelitian ini dipilih menggunakan metode total sampling, yakni seluruh ibu atau pengambil keputusan dalam rumah tangga dan berumur 20 hingga 65 tahun yang bersedia sebagai responden, didapatkan 60 responden yang memenuhi kriteria inklusi. Data dikumpulkan melalui wawancara menggunakan kuesioner dan diuji menggunakan Spearman. Mayoritas responden memiliki pengetahuan abatisasi yang rendah (46,7%) diikuti dengan perilaku penggunaan abate yang rendah (91,7%). Pengetahuan abatisasi tidak berhubungan signifikan dengan perilaku penggunaan abate, akan tetapi memiliki kecenderungan untuk berhubungan (p= 0,07). ABSTRACT Dengue hemorrhagic fever (DHF) is still a global health problem. Indonesia is the second largest position of DHF in the world. This study aimed to analyze the relationship between knowledge of abatization and abate usage behavior in Jatisari Village, Madiun Regency. This study was an observational analytic with cross-sectional design, was conducted in March 2019 - May 2020 in Jatisari Village, Madiun Regency, East Java. The population and sample in this study were selected using the total sampling method, including all mothers or decision makers in the household aged 20 to 65 willing years to be respondents, with 60 of them fulfilled the inclusion criteria. Data were collected through interviews using a questionnaire and processed by Spearman analysis. Majority of the respondents have a low abatization knowledge (46.7%) followed by low abate usage behavior (91.7%). The level of knowledge of abatization was not significantly related to abate usage behavior, but has a tendency to relate (p = 0.07).
POTENCY OF SOURSOP LEAF EXTRACT AND CURCUMIN WITH MAGNETIC AND MUCUS-PENETRATING NANOPARTICLE AS COLORECTAL CANCER ALTERNATIVE THERAPY Ebnudesita, Faiza Rahma; Dienanta, Savira Butsainah; Jannah, Ayik Rochyatul; I'tishom, Reny
Journal of Vocational Health Studies Vol. 5 No. 3 (2022): March 2022 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V5.I3.2022.186-191

Abstract

Background: Colorectal cancer is the second leading cause of death in the world. Currently, resection and adjuvant chemotherapy are the main therapies for colorectal cancer. Resection is an invasive procedure and chemotherapy often causes side effects due to non-specific work targets. Purpose: This study examines the potential of soursop leaf extract and curcumin with magnetic and mucus-penetrating nanoparticles as an alternative therapy for colorectal cancer. Review: Soursop leaf extract has acetogenin agent as an anti-tumor, anti-inflammatory, and cytotoxic agent that acts specifically on target organs. Curcumin from turmeric extract has antioxidant, anti-inflammatory, antimutagenic, antiangiogenic, and anticancer effects. Curcumin works molecularly on cyclooxygenase-2 (COX-2) to prevent inflammation, thereby inhibit the growth of cancer cells and reducing the risk of metastasis. Curcumin also plays a role in the inhibition of nuclear factor κ-light-chain-enhancer of activated B (NF-κB) cells, thus inhibits carcinogenesis. For drug delivery, magnetic nanoparticles and mucus-penetrating nanoparticles could be used. The magnetic field of magnetic nanoparticles generates force and torque to increase the temperature and movement of the organelles, so that apoptosis occurs from cancer cells. Mucus-penetrating nanoparticles are more resistant to mucus degradation because they can avoid mucoadhesive effects, penetrate the mucus adherent layer, and are easily absorbed by the intestinal epithelium. Conclusion: Soursop leaves, curcumin, magnetic nanoparticles, and mucus-penetrating nanoparticles are potential to be an alternative therapy for colorectal cancer.