Suwari, Cokorda Istri Padmi
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Junctional Bradikardia pada Pasien Hiperkalemia Suwari, Cokorda Istri Padmi; Puradipa, Bayu; Wulandari, Ni Luh Eka Sriayu
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1772

Abstract

Hyperkalemia is a life-threatening electrolyte abnormality resulting in cardiac arrhythmia. Hyperkalemia may also cause bradycardia with junctional rhythm. However, the prevalence of hyperkalemia accompanying symptomatic bradycardia has only been explored in a few case reports. Thus we present a case of hyperkalemia with uncommon ECG findings. It has been reported that a 76 years old woman with type 2 diabetes mellitus, hyperkalemia and suspected coronary artery disease complaining about palpitation. Electrocardiography (ECG) showed junctional bradycardia with tall T wave and laboratory examination showed mild hyperkalemia (5.8 mmol/L). After one day of observation, severe hypotension was detected. Unexpectedly the cardiac rhythm was returned into the sinus after correction of hyperkalemia using calcium gluconate, insulin, dextrose, and salbutamol. As serum potassium level rises, sinoatrial and atrioventricular conduction was blocked, causing escape rhythm (junctional escape rhythm). In hyperkalemia, cardiotoxicity can be caused by an increase in resting membrane potential, decreased depolarization and duration of depolarization. When detected on ECG, hyperkalemia should be treated urgently and important to identify underlying causes or precipitating factors of hyperkalemia. Sinus node dysfunction is not excluded in this case.  Hyperkalemia can present a bradycardia junctional rhythm. Although the increasing serum potassium levels were low, hyperkalemia may have affected the conduction system leading to the ECG changes.Keywords:  hyperkalemia, junctional bradycardia, symptomatic bradycardia
Efek Loading Statin Intensitas Tinggi Sebelum Intervensi Koroner Perkutan pada Pasien Sindrom Koroner Akut: Systematic Review Suwari, Cokorda Istri Padmi; Claudia, Mutiara
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2244

Abstract

Percutaneous Coronary Intervention (PCI) is one of the essential methods for Acute Coronary Syndrome (ACS) treatment, but this procedure has serious complications. Early loading dose statin has a favorable prognostic impact on patients undergoing PCI. However, this effect is still unclear.Objective: To evaluated the effect of loading high-intensity statin on Major Adverse Cardiac Events (MACE) before PCI in patients with ACS. Methods: Randomized controlled trials were conducted using databases from  CENTRAL, PubMed, Science Direct, and British Medical Journal. Then, titles, abstracts, and full texts were screened using the inclusion criteria to filter out irrelevant studies. Quality assessments were undertaken using the Jadad scale, and the results were narratively synthesized and presented in tables. Results: Seven studies were included in this systematic review after screening 1037 records. Four studies demonstrated a statistically significant reduction in MACE in the groups that received loading dose atorvastatin or rosuvastatin before PCI, compared with the comparator groups (p < 0.05). Conclusion: Loading high-intensity statin before PCI seems to be highly effective in reducing MACE in patients with ACS.Keywords:  acute coronary syndrome, major adverse cardiac events, percutaneous coronary intervention 
Mitral Stenosis Berat pada Penyakit Jantung Rematik Suwari, Cokorda Istri Padmi; Gede, Widyawati Desak
Jurnal Kesehatan Andalas Vol. 12 No. 2 (2023): Online July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v12i2.2245

Abstract

Rheumatic Heart Disease (RHD) has high morbidity and mortality. Cardiac valve disorders after rheumatic fever are the leading cause of heart failure in children and young adults. A comprehensive understanding of RHD can help early diagnosis and provide optimal management in the future. It has been reported that a 55-year-old man came to the heart clinic of Bhayangkara Hospital Denpasar for routine control of heart disease. The patient has been diagnosed with rheumatic heart disease since 2018. The patient complains of shortness of breath when walking long distances and doing strenuous activities. The patient was diagnosed with CHF FC II ec RHD + MS moderate-severe (Wilkins score 8) + AF NVR (CHA2DS2VASc 3) and treated with heart failure and antiplatelet medication. Mitral stenosis due to RHD produces the typical pathological features seen in Transthoracic echocardiography (TTE), including fibrous thickening and calcification of the valve leaflets, fusion of the commissures, and thickening and shortening of chordae tendineae. Chronic stress overload on the LA due to MS can cause LA dilatation and trigger AF. RHD patients with AF are recommended for anticoagulation for stroke prevention. Patients with acute rheumatic fever clinical features should be evaluated further and given long-term therapy to prevent more severe heart problems.Keywords:  atrial fibrillation, mitral stenosis, rheumatic  heart  disease