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All Journal Indian Journal of Forensic Medicine & Toxicology Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Marwa Karim Taha
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Health Professions Nursing Public Health

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Induced Hyperlipidemia in Adult Male Rats and Treated by using Rosmarinus officinalis Aqueous Extract Marwa Karim Taha; Mohammed Salman Dalas; Ahmed Hamad Saleh
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16750

Abstract

The current work was goaled to revealed anti-hyperlipidemia activity of R. officinalis extract. This workutilized 20 male rats that divided to negative group; positive group was given drinking water containing0.5% H2O2 and (1%) cholesterol for 60 days. Third group: hyperlipidemia rats were treated with (50mg/kg/daily) extract. Fourth group: hyperlipidemia rats were treated with (100mg/kg/daily) extract. Theoutcomes revealed significant (P < 0.05) rise in cholesterol and triglyceride and reduce the HDL in positivegroup compare with negative group. Malonedialdehyied (MDA) was increased with reduce in glutathione(GSH) compare with negative group. Otherwise, diameters of aorta artery show significant (P < 0.05) risecompare with negative group. R. officinalis aqueous extract when used in treatment, the outcomes exhibitedimprovement in lipid profile, MDA, GSH and diameters of aorta artery compare with negative group. It wasconcluded that R. officinalis extract possess anti-hyperlipidemia activity.
Effect Of Lowing Long-Term Levels Of Ionizing Radiation On Some Of Physiological Parameters and Oxidative Stress Among Radiologic Technologists Marwa Karim Taha; Asaad Taha Al-Douri; Haifa Saeed Lattif
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1246

Abstract

Technicians in radiology departments are continuously exposed to ionizing radiation, which can affect biological systems. This study aimed to investigate the effects of low-level ionizing radiation (IR) on antioxidant enzymes and blood components in radiology personnel. The study involved forty participants aged 30 to 45 years, divided into three groups: G1 as the control group (n=10), G2 consisting of 15 radiologists, and G3 comprising 15 radiology technology workers. Participants in G2 and G3 had work experience ranging from 5 to 15 years and were employed in X-ray and CT scan departments at General K1 Hospital, Kirkuk. The measured parameters included white blood cells (WBCs), platelets, and lymphocytes, as well as malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (TAC), and albumin as indicators of redox status. The results showed a significant increase in MDA levels among radiology workers compared to the control group, while SOD, TAC, and albumin levels decreased (P<0.05). Additionally, radiation-exposed workers had a higher mean count of WBCs and lymphocytes than the control group (P<0.05), whereas platelet levels were significantly lower (P<0.05). This study indicates that occupational radiation exposure can cause short-term changes in blood cells and increase the circulating redox state in healthcare workers operating in CT and IR environments compared to those not exposed to radiation. These findings highlight the importance of regular health monitoring for radiology personnel to mitigate potential long-term effects of radiation exposure.
Co-Authors Ahmed Hamad Saleh Asaad Taha Al-Douri Haifa Saeed Lattif Mohammed Salman Dalas