Nihad Khalawe Tektook
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Correlation between Interleukin(IL-6) and Procalcitonin (PCT) Level among Diarrheal Children Nihad Khalawe Tektook; Ahmed Salim Hadi Al-Khafaji
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16760

Abstract

This study was conducted his study was conducted in Baghdad for the period from December 1, 2019to June 3, 2020 for determination of the level of elevation of interleukin-6 and procalcitonin in childrenwith acute diarrhea, I was included 50 children suffering from diarrhea and 50 children without any otherdisease, where the ages of children in both groups ranged from one month to five years. The study includedcollecting information from children in both groups, including gender, age, living situation, number offamily members, standard of living and social as well as the number of family members, number of roomsin the house. Amount of 5 ml of blood samples were collected from all the children included in this study,where the blood samples were separated by the centrifuge device and the serum samples were separatedfrom them and kept in the refrigerator until the tests for detecting the level of Interleukin 6 and procalcitoninusing ELISA technique. In this study, 76 % of diarrheal children were suffered from abdominal pain, 68%with dehydration, 58% of fever, 46% had vomiting.The presented study found that, 78% of families withdiarrheal children were lived in crowed houses, 73% didn’t wash vegetables before eat, 69% haven’t wahhands, 66 used tap water for drinking.In this study, IL-16 was observed in elevated mean in diarrheal children(19.66±2.19 ng/ml), when it compared with the control healthy children (4.27±1.46 ng/ml) (P<0.001).In thisstudy, procalcitonin was also observed in elevated mean in diarrheal children (42.17±9.28 ng/ml), whenit compared with the control healthy children (28.19±8.27 ng/ml) (P<0.001).The study showed that themaximum means of PCT and IL-6 in diarrheal children were observed in those with fever, followed byabdominal pain. The study revealed a significant positive correlation between IL-6 and PCT level amongdiarrheal children.Conclusions:The study showed a significant relation of PCT and IL-6 with diarrhea..
Using of Procalcitonin Level in Differentiation between Bacterial Vaginitis Due to Pathogenic Bacteria and Normal Flora Eman Ghadhban Salih; Mohammed Ismael Dawood; Nihad Khalawe Tektook
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14591

Abstract

This study conducted to view the role of PCT level in initial finding of bacterial vaginitis in pregnantwomen. A total of 150 deep vaginal swabs (100 pregnant women and 50 pregnant women as controlgroup) were collected from the beginning of February 2019 to the end of May 2019 from inpatients andoutpatients women attended to Al-Fallujah teaching hospital. Media were organized & purified according toproducer’s guidance. The ready media were utilized for segregation , definition of the viable enumeration, identifying & sensibility workout these media were achieved in the wake of being solidified. Swabs wasinoculated bacteriological agars for isolation of causative bacterial types . Blood samples collected by veinpuncture for determination of PCT by using ELISA technique. The study showed that that 57% of pregnantwomen have vaginal swab for culture as compared with 48 of the control group (non- pregnant women). Theresults demonstrated that, 54.39% of pathogenic bacteria isolated from vagina of pregnant women was G-vebacteria and 45.61% was G+ve bacteria. S. aureus represented the highest rate of pathogenic isolates 45.61%in cases (43.86%) while 29.17 of the control group were infected equally by E coli and K. pneumonia.Thehighest rate of antibiotic sensitivity toward S. aureus isolates was occurred in levofloxacin (88.46%) whileit was completely resistant to ampicillin and lincomycin, 94.11% of E. coli isolates was sensitive to each oflevofloxacin and cefotaxime and 100% resistant to lincomycin, 92.85% of Klebsiella isolates was sensitive toamoxicalve while it was 100% resistant to ampicillin, erythromycin and lincomycin. Procalcitonin level washighly elevated among pregnant ones followed by healthy ones (26.79±9.4 v.s 9.236±0.6 pg/ml) at P value<0.01. The highest mean of Procalcitoninlevel is found among pregnant women with pathogenic bacteriaisolates of HVS culture (30.15±9.84 pg/ml) and the lowest mean is recorded among pregnant women withnormal flora isolates (23.72±7.25 pg/ml).Conclusions: Serum PCT was highly elevated in pregnant womenwith vaginitis especially who diagnosed with pathogenic bacteria.