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All Journal Indian Journal of Forensic Medicine & Toxicology
Orapin Insuan
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Public Health

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Effect of Thunbergia Laurifolia Lindl. on Oxidative Stress and Blood Cholinesterase in farm Workers Exposed to Pesticides in the Mae Chai District of Phayao Province Orapin Insuan; Padchanee Sangthong; Pennipat Nabheerong; Surachat Buddhisa; Peerawan Kengsangunsit; Suntorn Prompao; Benchaluk Thongchuai
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17014

Abstract

Thunbergia laurifolia Lindl. or Rang Chuet is a plant traditionally used in Thailand for the treatment oftoxicity and as an antidote for many poisons. This study aimed to investigate the effect of Rang Chuetcapsules on blood chemistry in 39 agricultural workers (21 males, 18 females) during an intensive 8-weekspraying program. The following tests were performed: serum butyrylcholinesterase (BChE) and serummalondialdehyde (MDA) levels before and after Rang Chuet capsule supplementation. The results indicatethat serum BChE levels were unchanged in male and female workers. However, the levels of serum MDAin male and female workers decreased significantly at p < 0.001 and p < 0.05, respectively. In this study, thephylogenetic relationships within the large tropical and subtropical family Thunbergia were studied usinggenomic DNA from the fresh leaves of sampled plants. The results showed 99% homology with Thunbergiacoccinea. This study indicates that Rang Chuet presents antioxidant activity and could be promoted as ahealth supplement.
Co-Authors Benchaluk Thongchuai Padchanee Sangthong Peerawan Kengsangunsit Pennipat Nabheerong Suntorn Prompao Surachat Buddhisa