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All Journal Indian Journal of Forensic Medicine & Toxicology
Yahya A. Altufaily
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Public Health

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Febrile Seizures in Thalassemic Patients in Babylon Teaching Hospital for Maternity and Children Yahya A. Altufaily; Hakim Yosif Radhi; Laith Jasim khejani
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17233

Abstract

Febrile seizures are the most common seizures in children. Their incidence is (2-5 %). To date, thepathophysiology of febrile seizures is unknown. But several hypotheses have been supposed that itmay relate with plasma iron level. Such low risk in thalassemic patients whose plasma iron level is highcould give some clues to this hypothesis.Aim of the Study: Determine the risk of febrile seizure in thalassemic patients in comparism with thecorresponding control group.Patients and Methods: This case –control study was conducted on one hundred fifty patients withthalassemia major between six month and six years of age who were visit Babylon center for inheritedblood diseases in the Teaching hospital for maternity and children from April 2019 to January 2020.All medical records of thalassemic patients were thoroughly reviewed and the occurrence of febrileseizures are interviewed and compared with the control group .The children in the control group areneither thalassemic nor has iron deficiency anemia.Results: Febrile seizure was detected in one case of the thalassemic group (0.66%) versus six cases(4%) of the control group. The risk of febrile seizure in the control group was 6 times more than that inthe thalassemia group, which was statistically significant (P =0.036).Conclusion: The risk of febrile seizures in thalassemic patients was (0.16) that of the general childrenpopulation. Thus, iron overload may be a major factor involving the brain metabolism that preventsfebrile seizures.
The Relation between Type One Diabetes Mellitus and Occurrence of Celiac Disease in Patients with in Babylon Teaching Hospital for Maternity and Children Hakim yousif Radi; Yahya A. Altufaily; Ali Sami Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16263

Abstract

Although the association between type 1 diabetes mellitus and celiac disease is well known, the presentingfeatures and clinical characteristics of the two diseases, when they coexist, are less well documented sothe study aimed to Estimate the incidence of celiac disease among patients attended to diabetic clinic inthe Babylon maternity and pediatric teaching hospital. Include retrospective study involves patients withT1DM attending the pediatric diabetic clinic in the Babylon maternity and pediatric teaching hospital, werescreened for celiac disease by serological testing for celiac antibodies (tissue transglutaminase). Controlgroup without diabetes mellitus were also been evaluated. The control group are those who were admitted tothe hospital for other diseases like gastroenteritis or chest infection, have no past medical history or chronicillnesses, and have no diabetes mellitus neither symptoms nor abnormal blood investigation results. Of the50 patients with T1DM and 50 without diabetes mellitus, 3 patients (6%) of the study group tested wereantibody positive. Celiac disease presented atypically in the majority of cases with an unpredictable intervalbetween diagnosis of diabetes and celiac disease presentation. In this study, we found that patients withclassical symptoms of celiac disease, (diarrhea, anorexia, abdominal distension, foul smelling stool, shortstature, unexplained hypochromic anemia), may have negative screening for celiac disease, while those withpositive screening test, were asymtomatic.
Co-Authors Ali Sami Mohammed Hakim Yosif Radhi Hakim yousif Radi Laith Jasim khejani