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INTERAKSI OBAT PENGGUNAAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA qosim, julaeha
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 2, No 2 (2017)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v2i2.1181

Abstract

Skizofrenia merupakan suatu penyakit psikiatrik kronis yang paling banyak menimbulkan masalah secara psikologis maupun sosial. Penyakit ini memerlukan terapi pemberian antipsikotik dalam waktu yang cukup lama yang diberikan secara tunggal maupun kombinasi, sehingga sangat mungkin dalam proses pengobatan dapat ditemukan interaksi obat dalam penggunaan antipsikotik. Penelitian ini bertujuan untuk mengetahui profil demografi pasien, profil penggunaan antipsikotik, dan untuk menganalisa interaksi obat penggunaan antipsikotik pada pasien skizofrenia di RS X. Penelitian ini merupakan penelitian observasional dengan rancangan cross sectional deskriptif. Pasien yang dilibatkan dalam penelitian ini adalah pasien skizofrenia di Rumah Sakit X periode 2007-2009 yang memenuhi kriteria inklusi, jumlah pasien yang diambil dalam penelitian ini adalah sebanyak 300 pasien dengan metode stratified sampling. Pengambilan data dilakukan secara retrospektif melalui rekam medik meliputi karakteristik pasien dan data penggunaan obat. Dari data yang ada didapatkan mengenai profil pasien, profil penggunaan antipsikotik (jenis, dosis, cara pemberian) yang diberikan secara tunggal maupun kombinasi. Hasil penelitian menunjukan bahwa pemberian kombinasi klorpromazin dan haloperidol, merupakan antipsikotik yang paling banyak digunakan untuk pengobatan skizofrenia dengan persentase selama periode 2007,2008, dan 2009 yaitu 60 %, 70 %, dan 47 %. Persentase interaksi obat penggunaan antipsikotik pada periode 2007, 2008, dan 2009 yaitu 100 %, 99 % dan 96.97 % interaksi obat.
DAMPAK PROGRAM TERAPI RUMATAN METADON (PTRM) TERHADAP PASIEN PTRM DI SATELIT PELAYANAN PTRM PROVINSI DIY qosim, julaeha
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 1, No 1 (2016)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v1i1.279

Abstract

Background: Methadone Maintenance Treatment Program (MMTP) is one of the harm reduction program due to injecting drug use. The purpose of MMTP is replacing the use of narcotics (heroin) injection, was replaced with the use of oral methadone. MMTP expected to reduce drug use, risk behavior, crime, and increase productivity, housing conditions, and family support for injecting drug users (IDUs). MMTP in Yogyakarta has been implemented since 2006. Currently have been provided four MMTP satellite services are: Grhasia hospital, Gedongtengen primary health care (PHC), Umbulharjo I PHC and Banguntapan II PHC. As of November 2012 there were 39 actively registered patients (35 males, 4 females). Thirty-two patients voluntarily participated in this study. Objective: To determine the impact of MMTP on patients, including a reduction in drug use, risk behavior, crime, and increase productivity, housing conditions, and family support in the MMTP satellite services Yogyakarta. Method: Descriptive research with case study design and cross-sectional approach. This research conducted in October - December 2012. Subjects were 32 MMTP active patients. The independent variable is implementation of MMTP services and dependent variable is the impact of MMTP. The research instruments use questionnaires and interview guides. The data source are patient’s medical record, MMTP active patients, and MMTP teams (physicians, nurses, and pharmacists). Analysis of descriptive data in the form of percentage achievement of MMTP impacts on patients and pearson correlation analysis to determine the relationship between MMTP services with the impact of MMTP on patients. Result: thirty-two (100%) patients had been decrease in their criminal behaviour since admission to the MMTP. Seventeen (53%) patients they were not using alcohol and/or drug since their admission in the MMTP. The analysis result of Pearson correlation was found significance level of 0,001 (< 0,05). With relationship value of 0,588. There was a significant positive relationship between  MMTP services with the impact of MMTP on patients. Conclusion: MMTP is useful in harm reduction due to injecting drug use. to improve counseling services in MMTP, MMTP teams should make scheduling of counseling time.