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All Journal Journal Of Vocational Health Studies Jurnal Riset Kefarmasian Indonesia
Pratiwi, Jati
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN MANGGA KASTURI (Mangifera casturi Kosterm.) Lestari, Dwi; MA, Muthia Dwi; Pratiwi, Jati; Saputri, Lidya Handoko
Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i3.169

Abstract

Mangga Kasturi (Mangifera casturi Kosterm.) is one of the plants in Indonesia that has potential as an antioxidant. The purpose of this study was to determine the IC50 value and antioxidant potential of the ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.). The ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.) was extracted using maceration with 96% ethanol as solvent. The antioxidant activity test was carried out using the DPPH (1,1-Diphenyl-2-Picrylhydrazil) method using a UV-Vis spectrophotometer and vitamin C as a comparison. The results of phytochemical screening tests on ethanol extracts showed positive secondary metabolites such as alkaloids, flavonoids, tannins, and quinones. Testing the ethanol extract of Mangga Kasturi leaves (Mangifera casturi Kosterm.) with the DPPH method showed that the ethanol extract had an antioxidant activity with an IC50 value of 83.61 ppm in the strong category of antioxidant potential.
FORMULATION AND TEST OF ANTIBACTERIAL ACTIVITY OF EMULGEL ESSENTIAL OIL OF CITRONELLA (CYMBOPOGON NARDUS (L.) RENDLE) AND ALOE VERA (ALOE VERA (L.) BURM. F.) EXTRACT AGAINST PROPIONIBACTERIUM ACNES Ratna Dewi, Sinta; Ressandy, Sylvan Septian; Handoko, Lidya; Pratiwi, Jati; Rahmah, Widya
Journal of Vocational Health Studies Vol. 6 No. 3 (2023): March 2023 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V6.I3.2023.158-164

Abstract

Background: Acne is described as an abnormal skin condition caused by the disruption of excess oil production and collaboration with bacteria. Aloe vera and citronella oil are plants that have antibacterial properties, including acne-causing bacteria. Purpose: To obtain a formulation that has an anti-acne effect. Method: This research method is experimental in which the formulation of citronella oil emulgel and aloe vera extract is made as much as 10-15 grams in each formula by varying the additional ingredients in each formulation. This formula was made from three different concentrations (F1 (6%:4%), F2 (4%:6%), and F3 (5%:10%)) and tested the physical stability, among others, organoleptic, pH, homogeneity, dispersion and antibacterial activity against Propionibacterium acnes. Result: There was no significant difference between the organoleptic test, pH, homogeneity, and inclusion in the eligible category. In contrast, the dispersion test had a slight difference in F2 and F3, which did not meet the requirements. Conclusion: Inhibitory activity test of the preparations obtained the average diameter of citronella oil emulgel preparations and aloe vera extract at concentrations of F1 (6%:4%), F2 (4%:6%), and F3 (5%:10%) are 11 mm, 10.7 mm and 16 mm and the ability to inhibit bacteria by all concentrations was in a strong category. Among the three formulations known to have the most remarkable effectiveness was at F3 (5%:10%) with an inhibitory diameter of F3 16 mm.
Co-Authors Dwi Lestari Handoko, Lidya MA, Muthia Dwi Rahmah, Widya Ratna Dewi, Sinta Ressandy, Sylvan Septian Saputri, Lidya Handoko