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Well Differentiated B3 Thymoma complicated with Vena Cava Superior Syndrome undergo Debulking and Chemotherapy Semara Putra, Wayan Wahyu; Noor Chozin, Iin; Wantry, Kenty; Isharanto, Artono; Erawati, Rachma Dini
Malang Respiratory Journal Vol. 2 No. 01 (2020): Shape the Curves
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2020.002.01.4

Abstract

Background: Thymoma is a rare neoplasm. This incident is comparable to 390 new cases reported per year. Genetic factors are believed to be one of the factors of B3 thymoma and thymus carcinoma. Multimodality of thymoma therapy (surgery, radiation and chemotherapy) gives better results.Case Report: Mr A, 29 years old, with initial diagnosis of stage IV thymoma (according to Masaoka) with SVKS then undergo debulking, followed by chemotherapy with a regimen of Cisplatin + Vincristin, Cyclophospamid, Doxorubicin, Prednison every 21 days as much as 6 times. Subjective responses indicated by reduced complaints of chest pain and loss of swelling of the right arm. Semisubjective response indicated by increase of body weight. Objective response is progressive, so can be continued with second line chemotherapy or radiotherapy.Conclusion: The prognosis of patient with well differentiated thymic carcinoma stadium iv (thymoma b3) complicated with vena cava superior syndrome was poor because of the objective response of the chemotherapy was progressive, and the relapse case was higher.
“A Rare Case of Post-Tuberculosis Proximal Tracheal Stenosis with Suspected Tracheobronchial Mycosis: Case Report” Tenaya, Nyoman Adi; Semara Putra, Wayan Wahyu
Jurnal Impresi Indonesia Vol. 5 No. 1 (2026): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v5i1.7334

Abstract

Tuberculosis (TB) is one of the leading causes of death due to infectious diseases worldwide. Indonesia ranks second in global TB cases according to the 2024 TB report. Although TB treatment successfully cures most patients, post-TB complications in the respiratory tract can occur. Tracheal stenosis as a sequel to TB is a rare manifestation and often resembles asthma or other obstructive lung diseases. In addition to structural causes, opportunistic infections such as tracheobronchial mycosis should be considered. A 37-year-old man presented with progressive shortness of breath, wheezing, and a sensation of obstruction in the throat. The patient had a history of pulmonary TB, which was fully treated in 2016. Physical examination revealed wheezing in both lung fields, and a chest X-ray showed signs consistent with TB sequelae. Bronchoscopy revealed partial proximal tracheal stenosis accompanied by suspected tracheobronchial fungal infection. The patient received bronchodilator therapy, corticosteroids, and antifungal treatment, with clinical improvement within four days.