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All Journal Spektra: Jurnal Fisika dan Aplikasinya SAINSMAT: Journal of Applied Sciences, Mathematics, and Its Education
Koroma, Lahai
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Electrical & Electronics Engineering Energy Immunology & microbiology Materials Science & Nanotechnology Mathematics Physics

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Extraction and Characterization of 2-Isopropenyl-1-methoxy-7, 7-dimethyl-4, 9-imidazo-5-hydroxy pyrimidine called Alchorneinol from root bark of Alchornea hirtella used for the treatment toothache, and diarrhoea is Sierra Leone Koroma, Lahai; Kamara, L. M.; Freezer-Williams, Ronnie
SAINSMAT: Journal of Applied Sciences, Mathematics, and Its Education Vol. 10 No. 1 (2021)
Publisher : ACEND Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (728.741 KB) | DOI: 10.35877/sainsmat1012122021

Abstract

A new compound LK001 identified as 2-Isopropenyl-1-methoxyl-7, 7-dimethyl-4, 9-imidazo-5-hydroxy pyrimidine and named Alchorneinol has been extracted from the root bark of Alchornea hirtella plant. It was isolated using solvent-solvent extraction method from the powdered root bark of A. hirtella. The white powdered compound was slightly soluble in water, ethanol chloroform and tested positive for unsaturation. The compound LK001 contained Carbon, Hydrogen, Oxygen, and Nitrogen during elemental analyses. It also tested positive for the presence Hydroxide group thus making it slightly different from the already reported drug Alchorneine. The fragmentation patterns proposed from the Mass spectrum for Sample LK001 and by McLafferty rule support a new compound named Alchorneinol in the root bark extract. Itis therefore one of the active compounds responsible for the treatment of pain, particularly tooth ache, as purgative, stomach-ache and to treat tiredness after intoxication in Sierra Leone.
Extraction and Characterization of 2-Isopropenyl-1-methoxy-7, 7-dimethyl-4, 9-imidazo-5-hydroxy pyrimidine called Alchorneinol from root bark of Alchornea hirtella used for the treatment toothache, and diarrhoea is Sierra Leone Koroma, Lahai; Kamara, L. M.; Freezer-Williams, Ronnie
SAINSMAT: Journal of Applied Sciences, Mathematics, and Its Education Vol. 10 No. 1 (2021)
Publisher : ACEND Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35877/sainsmat1012122021

Abstract

A new compound LK001 identified as 2-Isopropenyl-1-methoxyl-7, 7-dimethyl-4, 9-imidazo-5-hydroxy pyrimidine and named Alchorneinol has been extracted from the root bark of Alchornea hirtella plant. It was isolated using solvent-solvent extraction method from the powdered root bark of A. hirtella. The white powdered compound was slightly soluble in water, ethanol chloroform and tested positive for unsaturation. The compound LK001 contained Carbon, Hydrogen, Oxygen, and Nitrogen during elemental analyses. It also tested positive for the presence Hydroxide group thus making it slightly different from the already reported drug Alchorneine. The fragmentation patterns proposed from the Mass spectrum for Sample LK001 and by McLafferty rule support a new compound named Alchorneinol in the root bark extract. Itis therefore one of the active compounds responsible for the treatment of pain, particularly tooth ache, as purgative, stomach-ache and to treat tiredness after intoxication in Sierra Leone.
Synthesis Process and Nutritional Evaluation of Plantain as a Supplementary Food for Toddlers in Sierra Leone: A Study Utilizing Biuret’s, Benedict’s, and Iodine Solution Test Koroma, Lahai; Senesie, James Kuiva; Baion, Florence Wuyah; Lukulay, Baindu Miata; Kallon, Massah Badiwuloi
Spektra: Jurnal Fisika dan Aplikasinya Vol. 9 No. 2 (2024): SPEKTRA: Jurnal Fisika dan Aplikasinya, Volume 9 Issue 2, August 2024
Publisher : Program Studi Fisika Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/SPEKTRA.092.04

Abstract

Research on developing plantain fruit into juice, jam, ice cream, and fritters as a food supplement for toddlers was conducted in Sierra Leone. The work was done at the Mosoudo section of Daru village, Jawie Chiefdom, in Kailahun District. Four bunches of plantains were harvested from Jawei Chiefdom and stored in Mosoudo. Two bundles of the raw plantain were peeled, dried, and ground into powder, while the other two left to ripen at room temperature for nine days. Test were conducted using Iodine solution, Benedict solution, and Biuret test to check the presence of starch, glucose, and protein, respectively, in both the powdered and ripe plantain. The ripe plantains were then made into juice, jam, ice cream, and fritters. Fifty  mothers/caregivers, along with their children, were randomly selected to evaluate the color, taste, smell, and texture of the four plantain products. The sensory evaluation results showed high acceptance levels: color (53.5%), taste (59.0%), smell (61%) and texture (59.9%). The results suggest that the project could successfully provide nutritious and appealing food supplements for toddlers in Sierra Leone. It was recommended that the government and NGOs promote the cultivation of plantains instead of importing food supplements for children in Sierra Leone.
Co-Authors Baion, Florence Wuyah Freezer-Williams, Ronnie Kallon, Massah Badiwuloi Kamara, L. M. Lukulay, Baindu Miata Senesie, James Kuiva