Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Cermin Dunia Kedokteran Jurnal Kedokteran Methodist
Manullang, Doharjo
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Procalcitonin Level is Correlated with Community Pneumonia Severity Manullang, Doharjo; Keliat, EN; Abidin, Alwinsyah
Cermin Dunia Kedokteran Vol 45, No 9 (2018): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (125.411 KB) | DOI: 10.55175/cdk.v45i9.607

Abstract

Procalcitonin ( PCT ) is a peptide consisting of 116 amino acids released by thyroid C cells in very low concentrations ( < 0.05 ng / ml ). Microbial infection will increase the expression of CALC - 1 gene causing release of PCT from cells. A cross-sectional research was done on 60 patients : 33 men, 27 women, age 52.47 ± 13.31 years with community pneumonia from July 2011 to June 2013. The objective is to determine the correlation between procalcitonin levels and severity of community pneumonia in Department of Internal Medicine, H.Adam Malik Hospital, Medan. The results were the percentage of PCT class I 18.3 %, class II 8.3 %, class III 16.7 %, class IV 56.7 %; 41.7 % have PSI scores ≤ 90, 25 % have PSI score 91-130 and 33.3 % have PSI score > 130. There is a statistically significant correlation between PCT levels and severity of community pneumonia (p =0.0001 somers'd test)Prokalsitonin adalah prohormon kalsitonin, berupa peptida 116 asam amino yang dilepaskan oleh sel C tiroid dalam keadaan normal dan konsentrasinya sangat rendah (<0,05 ng/ml). Infeksi mikroba akan meningkatkan ekspresi gen CALC-I yang menyebabkan lepasnya PCT dari sel. Penelitian observasional dengan metode cross sectional dilaksanakan pada 60 pasien pneumonia komunitas rawat inap (Juli 2011 s/d Juni 2013) di Departemen Ilmu Penyakit Dalam RS H. Adam Malik Medan, 33 pria dan 27 wanita dengan usia rata-rata (± SD) 52,47±13,31 tahun. Tujuan penelitian untuk mengetahui hubungan kadar prokalsitonin terhadap derajat dan beratnya pneumonia komunitas. Hasil penelitian menunjukkan bahwa persentase pasien dengan kadar PCT derajat I 18.3 %, derajat II 8.3 %, derajat III 16.7 %, dan derajat IV 56.7 %; pada 41.7 % pasien dijumpai skor PSI (Pneumonia Severity Index) ≤ 90, 25 % pasien dengan skor PSI 91-130 dan 33.3 % pasien dengan skor PSI > 130. Terdapat hubungan signifikan antara derajat skor PSI dengan peningkatan kadar PCT (uji korelasi Somers’d p=0,0001).
CHF ec STENOSIS AORTA ec RHD + PH SEKUNDER Manullang, Doharjo; Tarigan, Menang Bastanta; Simanjuntak, Salomo G U; Situmeang, Ivonne; Simanjuntak, Evi Rosa; Hutahaeng, Reinhard DJ
Jurnal Kedokteran Methodist Vol. 18 No. 1 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Stenosis is the most common valvular heart disease in Europe and North America with fear of calcification in the elderly (2-7% of the population> 65 years) while congenital aortic stenosis is usually caused by rheumatic heart disease which is now rare and usually found in young age. Classification of Aortic Stenosis. Classification of Aortic Stenosis can be divided based on the severity divided into 3 parts of mild, moderate, severe and very severe. Echocardiography modality is one of the gold standard tools for determining Aortic Stenosis which in echocardiography can capture Peak aortic jet velocity, the mean pressure gradient aortic valve area. The following is a case report of a 36 year old man with CHF ec Aortic Stenosis ec Rheumatic Heart Disease. This case was only diagnosed about 1 month ago with complaints of shortness of breath and chest pain. And the patient immediately went to RSMH for further treatment. This case was appointed for the management and preparation for surgery as a definitive therapy so that it is expected to give the best results in this patient
Co-Authors Alwinsyah Abidin, Alwinsyah Hutahaeng, Reinhard DJ Keliat, EN Simanjuntak, Evi Rosa Simanjuntak, Salomo G U Situmeang, Ivonne Tarigan, Menang Bastanta