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All Journal Acta Neurologica Indonesia Journal of Neurointervention and Stroke (JNeViS)
Darmawan, Octavianus
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Medicine & Pharmacology Neuroscience Public Health

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Marital Status As A Predictor of Amnestic Mild Cognitive Impairment in Indonesia Chandra, Fani Agusta; Darmawan, Octavianus
Acta Neurologica Indonesia Vol. 2 No. 01 (2024): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v2i01.22

Abstract

Introduction: Several modifiable risk factors have been identified as the predictors of amnestic mild cognitive impairment (aMCI). However, research focusing on factors beyond biological is limited. Marital status is a psychosocial factor with recognized impact on health that needs further exploration. Objective: This study aimed to evaluate the association between marital status and aMCI amongst older Indonesian population. Material and methods: This was a cross-sectional study of Indonesian Family Life Survey-5. The participants (≥60 years old), excluding individuals with functional dependency, were subdivided into two based on word list recall (WLR) score (cut-off<6.5). Sociodemographic, psychological factors, physical activity, and body mass index were included as predictors. Bivariate and multivariate analyses were conducted. Result: A total of 4287 participants were included. Significant associations were observed between low WLR score and older age, low education, low socioeconomic status, rural residential area, being unmarried, life dissatisfaction, no social engagement, negative affect, and obesity. Multivariate analysis revealed being unmarried was significantly associated with aMCI (AOR 2.38, 95% CI 1.014–5.589, p=0.046), along with older age, low education, low socioeconomic status, and obesity. Discussion: Being unmarried (never married, divorced, or widowed) is a significant predictor of aMCI amongst Indonesian older people. This finding can be explained by the marital resource model and the stress model. Conclusion: This nationwide study is one of the first to explore marital status as a potential yet underexplored factor of aMCI in Indonesia. Being unmarried is associated with an increased risk of aMCI, prompting different approaches in this population.
Improvement of Hemifacial Spasm Following Palliative Embolization of an Unruptured Cerebellar Arteriovenous Malformation Kastilong, Merlin Prisilia; Usman, Fritz Sumantri; Sani, Achmad Firdaus; Saputra, Gilang Nispu; Darmawan, Octavianus; Muin, Rahmi; Kurnia, Leny; Keneddy, Erman
Journal of Neurointervention and Stroke Vol. 1 No. 1: MAY 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.11.6

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Highlight: Cerebellar region's AVM and hemifascial spasm Embolization AVM and hemifacial spasm ABSTRACT Introduction: Posterior fossa arteriovenous malformations (AVMs) are uncommon, accounting for 7–15% of all intracranial AVMs. These malformations typically present with symptoms such as headaches, seizure, and intracerebral hemorrhage. Reports of hemifacial spasm–characterized by involuntary contractions of the facial muscles–as a presenting symptom of AVMs are extremely rare and usually occur only when the facial nerve is compressed. Case: A 35-year-old male presented with worsening left-sided hemifacial spasm, unresponsive to medication for around one year, followed by progressive headache and dizziness. T2-weighted MRI revealed contact between the facial nerve root and a tortuous posterior inferior cerebellar artery (PICA), along with an AVM in the left cerebellar hemisphere. Cerebral angiography demonstrated a left cerebellar AVM with feeding arteries from superior cerebellar artery (SCA) and PICA. The patient underwent successful embolization of the SCA using glue (n-BCA:lipiodol). An intraprocedural thrombus developed but was managed appropriately. Post-procedural cerebral angiography revealed recanalization of the basilar artery and left PICA, with a 30% reduction in nidus size. The hemifacial spasm improved significantly after embolization with an HFS-7 score reduction of six points in the first week post-procedure. Conclusion: Palliative embolization has shown potential in alleviating symptoms associated with hemifacial spasm and improving quality of life. Careful patient selection is essential to rule out secondary causes of hemifacial spasm and to identify underlying neurovascular contacts.
Co-Authors Achmad Firdaus Sani, Achmad Firdaus Chandra, Fani Agusta Fritz Sumantri Usman, Fritz Sumantri Kastilong, Merlin Prisilia Keneddy, Erman Kurnia, Leny Muin, Rahmi Saputra, Gilang Nispu