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All Journal Elektrika Jurnal Sosial dan Teknologi Journal Of World Science
Kurniawan Nugroho, Andi
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Humanities Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Journal : Journal Of World Science

 1 
Advancements In Stem Cell Therapy For Pulmonary Fibrosis: A Comprehensive Review With Vinski Protocol Vinski, Deby Susanti Pada Vinski; Quintosa, Jaime Rodriguez; Ibnu Hajar, Andi; Vinski, Natasha Cinta; Kurniawan Nugroho, Andi
Journal of World Science Vol. 4 No. 9 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i9.1503

Abstract

Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by scarring of lung tissue and limited treatment options, resulting in high morbidity and poor prognosis. Mesenchymal stem cell (MSC) therapy has emerged as a promising regenerative intervention due to its potential for immunomodulation, epithelial repair, and anti-fibrotic effects. This review synthesizes current clinical and observational studies involving human participants, highlighting the safety and preliminary therapeutic benefits of MSCs in managing PF and related pulmonary conditions. Several clinical trials involving patients with idiopathic pulmonary fibrosis and COVID-19-associated lung injury demonstrated favorable safety profiles and trends toward improved pulmonary outcomes. Additionally, observational findings from the application of the Vinski Protocol at Celltech Stem Cell Centre provide further support for the regenerative capabilities of MSCs. While current human studies are encouraging, further large-scale and long-term clinical trials are essential to validate the efficacy of MSC therapy and establish standardized treatment protocols for PF.
Application of Mesenchymal Stem Cell for Degenerative Disc Disease Susanti Pada Vinski, Deby; Siagian, Carles; Kurniawan Nugroho, Andi; Hardjo, Marhaen; Cinta Vinski, Natasha
Journal of World Science Vol. 3 No. 3 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i3.562

Abstract

During a person's life, the spine will experience continuous changes in response to physiological axial loads. Increasing age is also a cause of pathological degenerative changes. Degenerative disease of the spine is a condition that many people complain about and requires appropriate and effective treatment. Degenerative disc disease is the most common cause of low back pain and disability worldwide, involving people of all ages and socioeconomic statuses. This study aims to explain and analyze the effectiveness of Mesenchymal Stem Cell therapy in treating Degenerative Disc Disease. The research method used is a case study where  Mesenchymal Stem Cell therapy offers the potential to modify the natural recovery of Degenerative Disc Disease using stem cell-based technology. Case studies were carried out at the Vinski Regenerative Center clinic, on several patients. And the results are that stem cells have the potential to be an ideal non-surgical treatment for low back pain and degenerative disc disease, because of their ability to differentiate into various connective tissue cells and their ability to restore damaged tissue and the results of case studies have proven to tend to improve the condition. However, long-term clinical studies are still needed, specifically focusing on the safety and efficacy of stem cell therapy in degenerative disc disease.
Quantum Stem Cell Therapy for Recovery of Liver Disease Susanti Vinski, Deby; Schroeter, CA; Hardjo, Marhaen; Kurniawan Nugroho, Andi; Cinta Vinski, Natasha
Journal of World Science Vol. 3 No. 5 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i5.609

Abstract

Chronic liver diseases pose a significant global health challenge, necessitating the development of novel therapeutic strategies for liver regeneration and functional recovery. Mesenchymal stem cells (MSCs) derived from umbilical cord blood have emerged as promising candidates for liver regeneration due to their multipotent differentiation capacity, immunomodulatory properties, and paracrine effects. This study aims to investigate the efficacy, safety, and underlying mechanisms of stem cell therapy in the recovery and regeneration of liver tissue in patients with liver disease. The research method used is a case study where Mesenchymal Stem Cell therapy offers the potential to modify the natural recovery of Liver function using stem cell-based technology. Case studies were carried out on several Vinski Regenerative Center clinic patients. This review explores the therapeutic potential of umbilical cord blood-derived MSCs in promoting the recovery of liver function in preclinical and clinical settings. We discuss the mechanisms by which MSCs facilitate liver regeneration, including their ability to differentiate into hepatocyte-like cells, modulate immune responses, and secrete trophic factors that promote tissue repair. Preclinical studies demonstrate the efficacy of umbilical cord blood-derived MSCs in ameliorating liver injury, reducing fibrosis, and improving overall liver function. Challenges such as optimal dosing, timing of administration, and long-term monitoring remain to be addressed. Nevertheless, MSCs from umbilical cord blood represent a promising therapeutic approach for liver regeneration and hold great potential for improving outcomes in patients with liver disease.
From Vitality to Security: Stem Cells and Testosterone Supporting Health and National Defense with the Vinski Protocol Vinski, Deby Susanti Pada Vinski; Vinski, Natasha Cinta; Trofimova, Svetlana; Kurniawan Nugroho, Andi; Pujowaskito, Prihati
Journal of World Science Vol. 4 No. 11 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i11.1589

Abstract

The vitality and health of a nation’s citizens, especially its emergency and defense forces, are inseparable from national security. Regenerative and hormonal medicine is an exciting new field in performance medicine. This Phase 1 clinical trial assesses the safety and initial effectiveness of the Vinski Protocol, an innovative therapy involving umbilical cord-derived mesenchymal stem cells (UC-MSCs) in conjunction with testosterone optimization therapy. Twenty-five healthy men, aged 25-45 years, received three intravenous infusions of UC-MSCs and weekly testosterone cypionate for 12 weeks. Primary outcomes measured safety through adverse event monitoring and clinical laboratory profiles, and secondary outcomes were serum testosterone change, VO2 max, body composition, inflammatory markers (C-reactive protein [CRP] and interleukin 6 [IL-6]), and subjective vitality. The protocol was well-tolerated with no serious adverse events; 12% of subjects reported mild fatigue. Statistically significant changes were noted in testosterone level (+215 ng/dL, p < 0.01), lean mass (+2.1 kg, p < 0.05), VO2 max (+11.8%, p < 0.05), and decreases in CRP and IL-6 (p < 0.05). Energy and mental clarity also improved in subjects. These findings provide evidence for the feasibility and potential effectiveness of the Vinski Protocol as a dual regenerative-hormonal approach to increasing individual vitality and overall health resilience.
Co-Authors Budiani Destyningtias Carles Siagian, Carles Cinta Vinski, Natasha Edy Susilo, Edy Endang Jayati, Ari Hardjo, Marhaen Ibnu Hajar, Andi Pujowaskito, Prihati Quintosa, Jaime Rodriguez Schroeter, CA Setyati Budiningrum, Diah Sri Heranurweni Susanti Pada Vinski, Deby Susanti Vinski, Deby Trofimova, Svetlana Vinski, Deby Susanti Pada Vinski Vinski, Natasha Cinta Xaverius Kaparang, Stevanus