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Trofimova, Svetlana
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Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Stem Cell Therapy for Men’s Vitality in Supporting National Health and Defense: A Comprehensive Review and Meta-Analysis Vinski, Deby Susanti Pada; Trofimova, Svetlana; Pujowaskito, Prihati; Wibowo, Markus; Vinski, Natasha Cinta
Journal of World Science Vol. 4 No. 3 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i3.1317

Abstract

This comprehensive review and meta-analysis examines the efficacy of stem cell therapy in enhancing men’s vitality while supporting national health and defense systems. Patient care records served as the primary source of data for evaluation and analysis, ensuring that real-world clinical outcomes were robustly captured. The study also evaluated the quality assurance of stem cell products cultured by the integrated Celltech Stem Cell Centre Laboratory and Banking, affirming that these products meet stringent clinical standards. Findings indicate that stem cell therapy possesses significant regenerative potential, particularly in repairing damaged cells. Notably, several patients who underwent therapy at the Celltech Stem Cell Center experienced remarkable functional recovery. These results underscore the therapeutic promise of stem cells not only for individual patient recovery but also as a strategic component in enhancing overall public health and national defense readiness.
Perspective of Gene Therapy for Regenerative Medicine: The Future of Complex Disease and Regenerative Application Pada Vinski, Deby Susanti; Griffin, Darren; Trofimova, Svetlana; Vinski, Natasha Cinta; Parish, Elizabeth
Journal of World Science Vol. 4 No. 6 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i6.1429

Abstract

Recent breakthroughs in biotechnology have significantly advanced the potential to regenerate damaged human tissues. Innovations in stem cell science, genetic engineering, and tissue scaffolding have rapidly pushed the boundaries of regenerative medicine. Yet, numerous technical hurdles remain, particularly concerning the clinical application of gene therapy. Core objectives of gene therapy include enhancing protein synthesis within cells, suppressing overactive genes, and rectifying dysfunctional cellular mechanisms linked to disease. While viral vectors remain dominant in current clinical trials due to their effectiveness, they carry risks of immune reactions and pathogenicity. This has sparked increased interest in non-viral alternatives, which promise greater safety and versatility. Non-viral delivery methods utilize plasmid DNA systems and synthetic carriers to transport therapeutic genes and show great potential, especially when integrated with tissue engineering techniques. By combining these non-viral tools with regenerative approaches, researchers aim to more precisely control the spatial and functional behavior of introduced genes within the body. This review critically assesses the evolution and challenges of gene therapy within the broader scope of regenerative medicine, with an emphasis on emerging non-viral delivery systems and their translational promise.
Stem Cell Therapy for Chronic Fatigue Syndrome: A Promising Approach Pada Vinski, Deby Susanti Pada Vinski; Trofimova, Svetlana; Quintosa, Jaime Rodriguez; Nugroho, Andi Kurniawan; Schroeter, CA; Jovanovic, Stevan
Journal of World Science Vol. 3 No. 11 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i11.1231

Abstract

Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating condition marked by persistent fatigue, cognitive dysfunction, and chronic pain, severely affecting quality of life. This study explores the potential of mesenchymal stem cell (MSC) therapy as an innovative treatment for CFS. Using a qualitative descriptive design and case studies, data were gathered through interviews, medical record reviews, and observations of patients undergoing MSC therapy. The findings revealed significant improvements in fatigue, cognitive function, and physical well-being, with participants reporting better memory, concentration, reduced pain, and improved daily functioning. While some sleep disturbances persisted, their severity was reduced. These results highlight the potential of MSC therapy to alleviate CFS symptoms and enhance quality of life. Despite its promise, challenges such as high costs, regulatory hurdles, and the need for standardized protocols persist. Further research is required to confirm long-term efficacy and safety, contributing to the growing evidence for regenerative medicine in treating chronic conditions like CFS.
From Vitality to Security: Stem Cells and Testosterone Supporting Health and National Defense with the Vinski Protocol Vinski, Deby Susanti Pada Vinski; Vinski, Natasha Cinta; Trofimova, Svetlana; Kurniawan Nugroho, Andi; Pujowaskito, Prihati
Journal of World Science Vol. 4 No. 11 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i11.1589

Abstract

The vitality and health of a nation’s citizens, especially its emergency and defense forces, are inseparable from national security. Regenerative and hormonal medicine is an exciting new field in performance medicine. This Phase 1 clinical trial assesses the safety and initial effectiveness of the Vinski Protocol, an innovative therapy involving umbilical cord-derived mesenchymal stem cells (UC-MSCs) in conjunction with testosterone optimization therapy. Twenty-five healthy men, aged 25-45 years, received three intravenous infusions of UC-MSCs and weekly testosterone cypionate for 12 weeks. Primary outcomes measured safety through adverse event monitoring and clinical laboratory profiles, and secondary outcomes were serum testosterone change, VO2 max, body composition, inflammatory markers (C-reactive protein [CRP] and interleukin 6 [IL-6]), and subjective vitality. The protocol was well-tolerated with no serious adverse events; 12% of subjects reported mild fatigue. Statistically significant changes were noted in testosterone level (+215 ng/dL, p < 0.01), lean mass (+2.1 kg, p < 0.05), VO2 max (+11.8%, p < 0.05), and decreases in CRP and IL-6 (p < 0.05). Energy and mental clarity also improved in subjects. These findings provide evidence for the feasibility and potential effectiveness of the Vinski Protocol as a dual regenerative-hormonal approach to increasing individual vitality and overall health resilience.
Co-Authors Andi Kurniawan Nugroho Griffin, Darren Jovanovic, Stevan Kurniawan Nugroho, Andi Markus Wibowo Pada Vinski, Deby Susanti Pada Vinski, Deby Susanti Pada Vinski Parish, Elizabeth Pujowaskito, Prihati Quintosa, Jaime Rodriguez Schroeter, CA Vinski, Deby Susanti Pada Vinski, Deby Susanti Pada Vinski Vinski, Natasha Cinta