Claim Missing Document
Check
Articles

Found 2 Documents
Search

Effect of Snakehead Fish and Sea Cucumber Extract Administration on Mast Cell Infiltration, Interlukin-6 (IL-6), and Albumin Levels in Burns and Surgical Wounds Purwoko, Purwoko; Putro, Bambang Novianto; Hananto, Arif Zuhal Amin
Indonesian Journal of Anesthesiology and Reanimation Vol. 4 No. 1 (2022): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.679 KB) | DOI: 10.20473/ijar.V4I12022.1-5

Abstract

Introduction: Burn injury impairs almost every organ system, which causes significant morbidity and mortality. Meanwhile, the phases included in burn healing are inflammation, cell recruitment, matrix deposition, epithelialization, and tissue remodeling phase. Previous studies showed that snakehead fish and sea cucumber extract have these effects and are beneficial in burn and post-surgery wounds. Objective: This study aims to analyze the effect of snakehead fish and sea cucumber extract supplementation towards mast cell infiltration, IL-6, and albumin level in burn and post-surgery wounds. Methods: A double-blind randomized control trial was carried out at Dr. Moewardi Hospital Surakarta in November 2017 on 30 subjects, which were divided into 2 groups. Mast cell infiltration was observed on burn and post-surgery wounds colored with Toluidine Blue, while IL-6 and albumin were measured -blood, where both groups had comparable basic characteristics. Results: There was a statistically insignificant (p=0.835) higher increase in albumin level in the treatment group, while an insignificant (p=0.056) greater decrease also occur in the IL-6 level. The decrease in cell mast infiltration after treatment was also higher and not statistically significant (p=0.526). Previous studies showed that amino acids from snakehead fish play an important role in wound healing. Meanwhile, high EPA content in sea cucumber is due to its ability as an Echinodermata to regenerate tissue. It was also discovered that the results available about sea cucumber and sea snake extract on wound healing are different based on the skin condition after the use of the extracts. Conclusion: Snakehead fish and sea cucumber extract supplementation can increase albumin level, decrease IL-6 level and mast cell infiltration in burn or post-surgery wounds.
Bantuan Hidup Dasar Dan Edukasi Tatalaksana Nyeri Di Lingkungan Sekolah Menengah Atas Karanganyar Purwoko, Purwoko; Nugroho, Andy; Santosa, Sugeng Budi; Supraptomo, R. Th; Setijanto, Eko; Purnomo, Heri Dwi; Arianto, Ardana Tri; Thamrin, Muhammad Husni; Hananto, Arif Zuhal Amin; Ihsaniar, Aura
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 13, No 1 (2024): Mei
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v13i1.79286

Abstract

Keadaan kegawatdaruratan adalah suatu keadaan dimana korban akan mengalami kecacatan atau bahkan kematian, bila tidak mendapatkan pertolongan dengan segera. Salah satu jenis masalah kegawatdaruratan yang dapat menimbulkan kematian mendadak biasanya ditemui diakibatkan oleh henti jantung (cardiac arrest). Penanggulangan kegawatdaruratan merupakan aspek yang penting dan tidak terbatas pada tenaga medis terlatih. Nyeri adalah sensasi yang sangat tidak menyenangkan dan sangat individual yang tidak dapat dibagi dengan orang lain. Siswa Sekolah Menengah Atas (SMA) adalah pelajar yang menduduki masa pendidikan formal sebelum memasuki bangku perkuliahan. Masih minimalnya pengetahuan siswa SMA akan manajemen nyeri menyebabkan seringkali penanganan dan tindaklanjut mengenai keluhan nyeri tidak adekuat. Hal ini yang menjadi dasar dilakukannya kegiatan ini sehingga siswa SMA dapat lebih teredukasi dan dapat menangani kondisi nyeri dengan baik serta memberikan edukasi berlanjut terutama kepada masyarakat. Departemen Anestesiologi dan Terapi Intensif Rumah Sakit Umum Daerah Dr. Moewardi bermaksud mengadakan pelatihan tentang Bantuan Hidup Dasar (BHD) bagi masyarakat dalam lingkup wilayah SMA untuk melakukan BHD pada korban henti jantung dan memberikan penyuluhan terkait manajemen nyeri dengan harapan agar para peserta lebih teredukasi mengenai kondisi nyeri dan bagaimana cara menanganinya. An emergency is a situation where the victim will experience disability or even death if they do not receive immediate help. One type of emergency problem that can cause sudden death most commonly occurs due to cardiac arrest (cardiac arrest). Emergency management is essential and not limited to trained medical personnel. Pain is a very unpleasant and highly individual sensation that cannot be shared with other people. High School (SMA) students are students who complete a period of formal education before entering college. High school students lack knowledge about pain management, so treatment and follow-up regarding pain complaints are often inadequate. This is the basis for carrying out this activity so that high school students can be more educated, handle pain conditions well, and provide ongoing education, especially to the community. Department of Anesthesiology and Intensive Therapy, Dr. Regional General Hospital. Moewardi intends to hold training on Basic Life Support (BHD) for the community within the SMA area to carry out BHD for cardiac arrest victims and provide counseling regarding pain management with the hope that the public will be more educated about pain conditions and how to handle them.