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Ahmad H Asdie Ahmad H Asdie
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Thyrotoxic periodic paralysis: A case report Ahmad H Asdie, Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 02 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.689 KB)

Abstract

The paper presented two cases of periodic paralysis complicating Graves disease of the Indonesians. Clinical presentation and laboratory findings were concomitant with classical description of thyrotoxic paralysis in these cases. The precipitating factor in our cases is thought to be severe physic- al activities done several hours before paralytic attacks. Hypokalemi a probably also precipitates the episode of paralytic attack, but not convincing since without specific treatment of hypokalemia the paralysis recovered spontaneously. In one case, the periodic paralysis reappeared several time after treatment with anti-thyroid medication, but can be controlled with beta-blockers, propranolol 4 dd 20 mg. Key Words.. thyrotoxic periodic paralysis - Graves disease - beta-blockers - hypokalemia - Indonesians.
Hiperglikemia dan Komplikasi Akut Diabetes Mellitus Ahmad H Asdie, Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 03 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.179 KB)

Abstract

Diabetes mellitus is a chronic metabolic disorder due to relative or absolute deficiency of insulin. The disease may be characterized by acute symptoms and signs of insulin deficiency, which are called acute complications in this paper. Diabetes is also associated with chronic complications such as atherosclerosis, neuropathy, nephropathy, retinopathy, and cataract. The paper presented a brief review of the role of hyperglycemia in the development of complic ations in the diabetic patient. There is little controversy as to the necessity of insulin for therapy and for prevention of diabetic complications. Key Words: diabetes mellitus - insulin deficiency - hyperglycemia - metabolic disorder - lipoprotein
Hyperglycemia and chronic diabetic complications Ahmad H Asdie, Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 04 (1987)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (693.305 KB)

Abstract

The paper presented a brief review of the role of hyperglycemia in the development of complications in the diabetic patient. The chronic diabetic complications tend to occur in patients with longstanding diseases. Althoueh the exact mechanism responsible for the development of each complication is not fully clarified, the [actors such as accumulation 01 soronol derived from hyperglycemia through polyol pathway, glycoproteins, myo-inositol deficiency, glycosylated non-enzymatic proteins, ketogenesis, hyperlipidemia, increased adhesiveness of platelet and hyperviscocity are thought to play significant roles in the pathogenesis. If the degree of metabolic abnormalities can be reduced by dietary manipulation and insulin administration, the rate of development of diabetic complications should also be reduced. This hypothesis has been shown to be correct by several investigators. Others disagree with that. However, whatever the cause of the development of chronic diabetic complications were it is believed that diabetic control is important and that each diabetic patient should be encouraged to learn as much as possible about diabetes mellitus in that they will have a better understanding of the necessity as well as the desire for good control. If complete normalization of blood glucose and other metabolic abnormalities can not be achieved, the chronic diabetic complications will continue to occur. And in the severe cases, the result of the treatment may not influence the nature of the complications. Key Words: hyperglycemia - chronic diabetic complications - polyol pathway - glycosylated non-enzymatic proteins - metabolic abnormalities
Hyperglycemia and chronic diabetic complications Ahmad H Asdie Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 04 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (693.305 KB)

Abstract

The paper presented a brief review of the role of hyperglycemia in the development of complications in the diabetic patient. The chronic diabetic complications tend to occur in patients with longstanding diseases. Althoueh the exact mechanism responsible for the development of each complication is not fully clarified, the [actors such as accumulation 01 soronol derived from hyperglycemia through polyol pathway, glycoproteins, myo-inositol deficiency, glycosylated non-enzymatic proteins, ketogenesis, hyperlipidemia, increased adhesiveness of platelet and hyperviscocity are thought to play significant roles in the pathogenesis. If the degree of metabolic abnormalities can be reduced by dietary manipulation and insulin administration, the rate of development of diabetic complications should also be reduced. This hypothesis has been shown to be correct by several investigators. Others disagree with that. However, whatever the cause of the development of chronic diabetic complications were it is believed that diabetic control is important and that each diabetic patient should be encouraged to learn as much as possible about diabetes mellitus in that they will have a better understanding of the necessity as well as the desire for good control. If complete normalization of blood glucose and other metabolic abnormalities can not be achieved, the chronic diabetic complications will continue to occur. And in the severe cases, the result of the treatment may not influence the nature of the complications. Key Words: hyperglycemia - chronic diabetic complications - polyol pathway - glycosylated non-enzymatic proteins - metabolic abnormalities
Hiperglikemia dan Komplikasi Akut Diabetes Mellitus Ahmad H Asdie Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 03 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.179 KB)

Abstract

Diabetes mellitus is a chronic metabolic disorder due to relative or absolute deficiency of insulin. The disease may be characterized by acute symptoms and signs of insulin deficiency, which are called acute complications in this paper. Diabetes is also associated with chronic complications such as atherosclerosis, neuropathy, nephropathy, retinopathy, and' cataract. The paper presented a brief review of the role of hyperglycemia in the development of complic ations in the diabetic patient. There is little controversy as to the necessity of insulin for therapy and for prevention of diabetic complications. Key Words: diabetes mellitus - insulin deficiency - hyperglycemia - metabolic disorder - lipoprotein
Thyrotoxic periodic paralysis: A case report Ahmad H Asdie Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 02 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.689 KB)

Abstract

The paper presented two cases of periodic paralysis complicating Graves' disease of the Indonesians. Clinical presentation and laboratory findings were concomitant with classical description of thyrotoxic paralysis in these cases. The precipitating factor in our cases is thought to be severe physic- al activities done several hours before paralytic attacks. Hypokalemi a probably also precipitates the episode of paralytic attack, but not convincing since without specific treatment of hypokalemia the paralysis recovered spontaneously. In one case, the periodic paralysis reappeared several time after treatment with anti-thyroid medication, but can be controlled with beta-blockers, propranolol 4 dd 20 mg. Key Words.. thyrotoxic periodic paralysis - Graves' disease - beta-blockers - hypokalemia - Indonesians.
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