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Consequential Surgeries Limit Recurrence of Skin Malignancies in Xeroderma Pigmentosum: A Case Report Kurnia, Ahmad; Kartini, Diani; Herwirastri, Novinda; Adyasa, Zoya M
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Xeroderma Pigmentosum (XP) is a rare inherited skin malignancy with no causative treatment options. Reporting a 23-year-old woman with xeroderma pigmentosum who underwent several surgical tumor removals followed by further five procedures to apply tissue expander, facial resurfacing using full-thickness skin grafts with a donor from abdominal. The next series was tumor resection in the chin, forehead, nasal reconstruction, tumor removal on bilateral third digits, and defect closure. No recurrence after nine years of postoperative monitoring with an aesthetically acceptable result.
Recanalization Rates and Complications of Post-Endovenous Microwave Ablation in Chronic Vein Insufficiency with Large GSV Diameter Herwirastri, Novinda; Muradi, Akhmadu
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4763

Abstract

Endovenous Microwave Ablation (EMA) is one of the thermal ablation modalities to treat chronic venous insufficiency (CVI). The effectiveness and safety of EMAs in large-diameter saphena magna veins (GSVs) still require further research. This study aimed to compare the rates of recanalization and post-EMA complications in CVI patients with GSV diameters of <8 mm and ?8 mm. This retrospective cohort study used data from 54 patients from a multicenter (January 2023 – May 2025). Statistical analysis was performed with an unpaired t-test and a Chi-square test. The rate of venous occlusion reached 100% in both groups. The recanalization rate at 3 months post-procedure was higher in the GSV group ?8 mm (11.1%) compared to the GSV <8 mm (3.7%), although the difference was not statistically significant (p=0.299). There were no significant differences in complications of ecchymosis, thermal skin injury, and paresthesia. However, pain was reported to be significantly higher in the ?8 mm GSV group (33.3% vs 7.4%; p=0.018). The EMA is effective in achieving occlusion in a wide range of GSV diameters, but patients with a GSV of ?8 mm (especially ?10 mm) have a higher tendency to recanalize and post-procedure pain. Additional strategies are needed to be considered to increase effectiveness and comfort in the group.