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Faktor-faktor yang Mempengaruhi Daya Ingat Anak dengan Epilepsi Andreas, Scorpicanrus Tumpal; H Saing, Johannes; Prima, Cynthea
Cermin Dunia Kedokteran Vol 44, No 12 (2017): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.793 KB) | DOI: 10.55175/cdk.v44i12.688

Abstract

Abstrak. Daya ingat merupakan salah satu aspek kognitif terpenting. Obat anti epilepsi, faktor psikososial, dan komorbiditas pada epilepsi dapat menyebabkan gangguan daya ingat pada anak. Gangguan daya ingat harus dideteksi sedini mungkin agar dapat diintervensi untuk memperbaiki atau mencegah perburukan fungsi kognitif anak dengan epilepsi.Abstract. Memory is one of the most important aspect of cognitive function. Anti epileptic drugs, psychosocial factors, and comorbidity in epilepsy can cause memory impairment. Memory impairment should be detected as early as possible to allow intervention to improve or prevent cognitive worsening.
The Relationship Between Lipid Profile and the Incidence of Relapsing Nephrotic Syndrome in Children Tarigan, Utari Olivina; Siregar, Rosmayanti Syafriani; Lubis, Syamsidah; Fujiati, Isti Ilmiati; Deliana, Melda; Prima, Cynthea
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7017

Abstract

Nephrotic syndrome (NS) is one of the most common chronic kidney diseases in children, characterized by massive proteinuria, hypoalbuminemia, edema, and dyslipidemia. Relapse occurs in most cases and contributes to worsening the disease course. Dyslipidemia is suspected to influence relapse risk, but the specific relationship between lipid profile and relapsing NS remains unclear. Objective to analyze the association between total cholesterol, triglycerides, LDL, and HDL levels with relapse incidence in children with nephrotic syndrome. A retrospective study was conducted on 66 children aged 2–18 years with NS treated at H. Adam Malik General Hospital, Medan, in 2024. Subjects were divided into relapsing (n=54) and non-relapsing (n=12) groups. Data were obtained from medical records and analyzed using the Mann-Whitney test and Spearman correlation. Triglyceride (p=0.007), LDL (p=0.013), and HDL (p<0.001) levels differed significantly between the relapsing and non-relapsing groups. Total cholesterol showed no significant difference (p=0.164). The mean albumin level was significantly lower in the relapsing group (2.9 g/dL vs. 4.1 g/dL; p<0.001). A significant negative correlation was found between albumin and triglyceride levels (r=-0.326; p=0.008). Triglyceride, LDL, and HDL levels are significantly associated with relapse in pediatric nephrotic syndrome. Hypoalbuminemia is also an important risk factor. Lipid profile evaluation can serve as a useful indicator in monitoring and managing relapses.