Wulani, Vally
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Gambaran Radiologis Karsinoma Sel Skuamosa Mediastinum -, Biddulth; Wulani, Vally; Tanurahardja, Budiana; -, Wuryantoro
Cermin Dunia Kedokteran Vol 43, No 4 (2016): Adiksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (760.799 KB) | DOI: 10.55175/cdk.v43i4.47

Abstract

Dilaporkan sebuah kasus jarang, yaitu karsinoma sel skuamosa di mediastinum. Seorang laki-laki berusia 63 tahun, dengan benjolan di dinding dada yang makin membesar dalam 1 tahun terakhir. Pasca-biopsi, dilakukan radiasi eksterna untuk menghentikan perdarahan. Pada CT scan, didapatkan massa mediastinum, menginvasi struktur sekitar dan pembuluh darah. Pada pemeriksaan skintigrafi tulang, didapatkan tanda-tanda metastasis osteopeni. Pada pemeriksaan histopatologi biopsi didapatkan karsinoma sel skuamosa.
PENGARUH NILAI FRACTIONAL ANISOTROPY (DIFFUSION TENSOR IMAGING) PADA TERAPI IMPLANTASI KOKLEA DALAM KLINIS SENSORINEURAL HEARING LOSS (SNHL) Purnawati, Heny; Amanda, Mega; Wulani, Vally; Serfina Fajarini, Eunike
JRI (Jurnal Radiografer Indonesia) Vol. 3 No. 1 (2020)
Publisher : Perhimpunan Radiografer Indonesia (PARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.885 KB) | DOI: 10.55451/jri.v3i1.63

Abstract

Background: Diffusion Tensor Imaging (DTI) on current MRI cochlear examination able to support the diagnosis and help determine implantation therapy. The DTI line can show the cochlea tract and fractional anisotropy (FA) values with reference to the control reference value. DTI can visualize white matter in the cochlear tract that can be mapped in the FA of the entire cochlear image using directions. The FA value on the MRI cochlear examination can be used to determine the continuation of implant placement in the patient by using the FA-DTI value in the case of sensorineural hearing loss (SNHL). Method: Data were taken from September 2018 to August 2019. The MRI sequences used were Axial T2 5mm, Coronal T2 2mm, Axial T2 2mm, Axial 3D Fiesta-C 0.4mm and DTI 2mm. The total time of examination was 20 minutes using post processing Functool on the 2mm DTI results, measuring the region of interest (ROI) to obtain FA values ​​in several segments, namely region Trapezoid Body (rTB), region Superior Olivary Nucleus (rSON), region Inferior Colliculus (rIC), region Medial Geniculate (rMG), region Auditory Radiation (rAR). Result:The results of the DTI image are very sensitive to produce a diagnosis in the form of nerve fibers. DTI which is supported by the results of the FA score is able to provide quantitative information. Conclusion: There is an effect on the FA-DTI value in SNHL cases for cochlear implant therapy.
Skoring Risiko Mortalitas pada Pneumonia Komunitas Sedang-Berat Kusuma, Ni Nyoman Indirawati; Singh, Gurmeet; Wulani, Vally; Rumende, Cleopas Martin Martin; Fauzar, Fauzar; Kamelia, Telly; Koesnoe, Sukamto; Susilo, Adityo; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Introduction. Community Acquired Pneumonia (CAP) is a lung parenchyma infection acquired outside of the hospital and is significantly associated with morbidity and mortality rates. Identifying patients with moderate-severe CAP at high risk of mortality through a combination of these variables is expected to serve as a basis for prompt and appropriate intervention, ultimately improving clinical outcomes for CAP patients. This study aimed to develop a scoring system using clinical characteristics, radiological findings, and serum biomarkers to assess the mortality risk in patients with moderate-severe CAP. Methods. This study employs a retrospective cohort design with moderate-severe CAP patients treated at Dr. Ciptomangunkusumo Hospital, Jakarta. The sample data were secondary, derived from medical records of patients diagnosed with moderate-severe CAP between January 2022 and December 2023. Predictor variables for mortality risk were obtained through multivariate analysis using Cox regression. Results. The study included 277 subjects, with 124 (44.77%) deaths and 153 (55.23%) survivors. Predictor variables consistently influencing mortality risk in moderate-severe CAP patients were low BMI (HR 1.609, 95% CI 1.047 – 2.472), procalcitonin (HR 1.778, 95% CI 1.200 – 2.634), and lactate levels (HR 1.451, 95% CI 0.994 – 2.119). The prediction model’s performance, based on the ROC curve analysis, showed moderate predictive ability (AUC = 0.641), and calibration performance, as assessed by the Hosmer-Lemeshow test, showed good validation (p = 0.082). Conclusions. There is an association between BMI, procalcitonin, and lactate levels with the mortality risk in moderate-severe CAP patients. A mortality risk scoring model for moderate-to-severe CAP patients has been established.