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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran
Savio, Sherly Desnita
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Osteoporosis dan Terapi Bisfosfonat Savio, Sherly Desnita
Cermin Dunia Kedokteran Vol 45, No 7 (2018): Onkologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (628.961 KB) | DOI: 10.55175/cdk.v45i7.644

Abstract

Osteoporosis sering ditemukan dalam praktek sehari-hari di Indonesia. Osteoporosis memiliki karakteristik berupa penurunan densitas mineral tulang/ bone mineral density (BMD). Faktor risiko osteoporosis antara lain keturunan,diet rendah kalsium, merokok, konsumsi berlebihan alkohol dan kafein, penggunaan steroid jangka panjang, dan latihan fisik inadekuat. Untuk kelompok berisiko, disarankan pemeriksaan DXA untuk skrining dan diagnosis osteoporosis.Komplikasi osteoporosis antara lain fraktur vertebra, non-vertebra, dan pinggul.Terapi adalah bisfosfonat, khususnya yang mengandung nitrogen (alendronate, risedronate, ibandronate, zolendronate).Osteoporosis is a common problem found in daily practice in Indonesia. Osteoporosis is characterized by the decline in bone mineral density (BMD). Risk factors of osteoporosis contain family history of osteoporosis, low calcium diet, smoking, overconsumption of alcohol and caffeine, long term steroid usage, and inadequate physical activity. DXA examination for screening and diagnosis is suggested for high risk group. The complications of osteoporosis are vertebral, non-vertebral, and hip fractures. Therapies use bisphosphonate, especially nitrogen containing bisphosphonates (alendronate, risedronate, ibandronate, zolendronate).
Close Reduction Percutaneous Pinning (CRPP) versus Open Reduction Internal Fixation (ORIF) pada Fraktur Supracondylar Humerus Gartland Tipe II dan III pada Pasien Pediatri: Tinjauan Sistematis dan Meta-analisis Astawa, Putu; Maharjana, Made Agus; Adisthanaya, Surya; Putra, Made Winatra Satya; Putra, Agus Suarjaya; Savio, Sherly Desnita
Majalah Kedokteran Indonesia Vol 71 No 4 (2021): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.71.4-2021-389

Abstract

Introduction: Displaced supracondylar fracture in children is a challenging injury that may result in impaired functional and cosmetic outcome if not well-treated. Utilization of Closed Reduction and Percutaneus Pinning (CRPP) increased for this pathology, some authors believe ORIF results better anatomical reduction and lower rate of loss of reduction. Study aims to compare CRPP and ORIF for pediatric supracondylar humerus fracture. Method: Systematic review was conducted based on PRISMA guideline. Inclusion criteria were age less than 18 years old, comparing CRPP and ORIF for Supracondylar Humerus Fractures Gartland Type II, II.Studies of one surgical technique, Gartland type I, case reports were excluded. For meta-analysis, 6 studies were included and fixed effect model used to pool the result. In each study, mean difference (MD) with 95% confidence interval (CI) was calculated for dichotomous outcomes using Review Manager. Result: Total of 252 patients aged 0-15 years old were included. CRPP more often performed than ORIF. Satisfactory outcomes measured by Flynn’s criteria were achieved in 87.74% in CRPP and 86.73% in ORIF patient group, indicating significant difference (Heterogeneity, I2 = 23%; WMD, 1.26; 0.58 to 2.73; P =0.56). Conclusion: Current systematic review and meta-analysis suggest that for displaced supracondylar humerus fractures, ORIF offers a comparable functional and cosmetic outcome compared to CRPP.
Co-Authors Maharjana, Made Agus Putra, Agus Suarjaya Putra, Made Winatra Satya Putu Astawa Surya Adisthanaya, Surya