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Hypnosis for Pain Alleviation: Placebo or Nocebo? Rima Sutiono, Dias; Putra Gunawan, Jeremy; Devina, Astrella; Sindjaja, Wibi; Pavita, Jesslyn
Cermin Dunia Kedokteran Vol 46, No 2 (2019): Penyakit Dalam
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.779 KB) | DOI: 10.55175/cdk.v46i2.527

Abstract

The use of hypnosis to alleviate pain had started to gain recognition. In the assessed papers, application of hypnosis has included childbirth, surgeries, and chronic pain. In childbirth, the use of self-hypnosis can reduce the use of analgesics from 78% to 45% of cases. The satisfaction of hypnobirthing—birth using hypnosis—reaches 96%. Hypnosis can decrease the use of anesthesia drugs during surgery, promotes healing, decreases bleeding and hospital stay. Hypnosis can alleviate pain and reduce the use of over the counter painkillers; also showed benefits for non-cardiac chest pain relief while also reduces medication. Currently, hypnosis had been the most prominent application for labour pain relief. There is a demand for more studies of bioinformatics and neuroscience.Penggunaan hipnosis untuk mengurangi rasa sakit sudah mulai mendapat pengakuan. Banyak pustaka menjelaskan penerapan hipnosis pada proses melahirkan, operasi, dan nyeri kronis. Pada proses melahirkan, self-hypnosis dapat mengurangi penggunaan analgesik dari 78% menjadi 45% kasus. Kepuasan hypnobirthing – kelahiran menggunakan hipnosis - mencapai 96%. Hipnosis dapat mengurangi penggunaan obat anestesi, mempromosikan penyembuhan, mengurangi perdarahan dan lama rawat di rumah sakit pasca-operasi. Hipnosis bisa mengurangi penggunaan obat penghilang nyeri; juga menunjukkan manfaat untuk penderita nyeri dada non-jantung selain mengurangi konsumsi obat. Saat ini, aplikasi hipnosis yang paling menonjol untuk nyeri persalinan. Diperlukan studi bioinformatika dan neuroscience lebih lanjut.
Toxicity of the Organophosphorus Pesticide Temephos Satriawan, Dina Atrasina; Sindjaja, Wibi; Richardo, Timmy
Indonesian Journal of Life Sciences 2019: IJLS Vol 01 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (618.893 KB) | DOI: 10.54250/ijls.v1i2.26

Abstract

Dengue is a major public health problem in tropical urban areas, not only because it can quickly progress from the mild dengue fever to the deadly dengue hemorrhagic fever, but also because there is no single cure or licensed vaccine available to this day. To control the disease, the World Health Organization has recommended insecticides to control the number of mosquito vectors Aedes aegypti and Aedes albopictus. One of the main insecticides used is temephos, which inhibits the progression of the mosquito life cycle at the larvae stadium. Temephos is a member of the organophosphorus group of insecticides which is known to exhibit neurotoxicity through a common cholinergic pathway to insects and mammals. Despite its possible toxicity towards humans and other non-target organisms, temephos has been used widely to treat household water, including drinking-water and bath-water. Although clinical studies have yet shown any detrimental effects due to chronic consumption of temephos, studies on animal models have shown neurodevelopmental toxicity, while at the molecular level, exposure to tempehos has demonstrated genotoxic effects. Temephos is also considered an environmental contaminant and accumulation in soil and water have caused toxicity towards water organisms. Considering the extensive and repeated usage of temephos in public health, understanding and confirming the safety of temephos towards human health is crucial. Therefore, the objective of this paper is to review the current body of work available on the toxicity of temephos as a common dengue vector control.