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Penggunaan Antikejang Pada Cedera Kepala: Tinjauan Sistematis Nabila Zafira, Safa; Aulya Kemuning, Diva; Izzatush Sholihah, Nur; Nooradi Praramdana, Muhammad
Jurnal Syntax Fusion Vol 2 No 06 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : CV RIFAINSTITUT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.138

Abstract

Brain injury can occur due to direct head impact and injury due to brain tissue damage such as hypotension, hypoxia, acidosis and edema. Brain injury will trigger an inflammatory process that can lead to post-trauma seizures. The use of anti- epileptic drugs is intended as a seizure prophylaxis so that it can reduce the incidence of seizures in the early phase of injury. Quantify the effectivity of anti seizure usage on post traumatic seizure accident. The method used in this paper is a relevant systematic review from various references and focuses on the use of analgesics for the management of seizures due to brain injury. The literature search used PubMed and found 7 literature that met the criteria. Consists of 1 RCT study and 6 observational studies. Prophylactic therapy in the incidence of head injury is effective in preventing PTS. The use of anti seizure can be given to patients with moderate or severe TBI and can be given less than 12 hours after injury to prevent seizures. Prophylactic therapy is only recommended for 7 days after head injury. Anti seizure drug which is often used as a prophylactic agent are phenytoin and levetiracetam. Lacosamide is recommended for users with refractory status epilepticus. Levetiracetam has fewer side effects than phenytoin and lacosamide, so the use of this drug is preferable to use.Using Anti seizure in cases of post-traumatic brain injury (TBI) or post traumatic seizure (PTS) is behoof as a seizure prophylactic attempt by using recommendation less than eight days because OAE has been shown several side effects, include increasing mortality. Especially for using phenytoin and lacosamide, it is necessary to monitor
Literatur Review: Mata Kering Akibat Obat-Obatan Izzatush Sholihah, Nur
Jurnal Syntax Fusion Vol 2 No 04 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : CV RIFAINSTITUT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i02.158

Abstract

Dry eye disease is a disease that is often encountered and can occur due to several factors. This disease is more common in women than men. The risk factors that can cause dry eyes are divided based on individual characteristics, environment, chronic disease, autoimmune disease, medications and history of injury. The writing of this article was obtained from various sources in the form of scientific journals and guidelines for related institutions. Source searches were carried out on various online portals such as Medscape, NCBI, Google Scholar and other health websites with the keyword “Dry Eye Disease”, “Dry Eye Syndrome”, “Medications Causes Dry Eyes” Dry eye disease is a disease that is often encountered and occurs because it is multifactorial and can affect the quality of life and interfere with vision, especially when carrying out daily activities. One of the factors that cause dry eyes, namely the use of drugs, both topical drugs and systemic drugs. Concurrent use of five or more medications can increase the occurrence of dry eye. Management of dry eyes can be given artificial tears and stop using medications that trigger dry eyes or replace the drug with another drug. Dry eye disease can be caused by the use of drugs, both topical and systemic drugs. Treatment that can be done, namely by giving artificial tears and avoiding systemic or topical ophthalmic drugs that cause dry eyes.