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All Journal Indian Journal of Forensic Medicine & Toxicology
Adel M. Rabee
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Public Health

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Evaluation of Biomarkers in Workers Exposed to Air Pollutants in Oil Refineries Esraa H. mohammed; Adel M. Rabee
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17494

Abstract

Air pollution is nowadays a complex problem due to industrial prosperity. Among the chemical industry,oil refineries have been identified as major emitters of a wide range of pollutants, the workers of the oilrefinery are exposed to a great variety of toxic compounds. Air pollution is the main environmental causeof human disease and death. Therefore, it is necessary to develop early warning signals or biomarkersthat convincingly reflect adverse biological responses towards anthropogenic environmental toxinseven at minute concentrations. This work aims to study the effects of exposure to the air pollution of oilrefinery, on the parameter blood, TNF-a, antioxidant glutathione peroxidase(GPx), and oxidative stressmalondialdehyde (MDA), in workers of the oil refinery. Results showed that exposure to air pollutionin the oil refinery lead to( a significant increase in levels Hb, WBC, Lymphocyte, TNF-a, and MDA,decrease levels of GPx) P<0.05. And non –significant in( RBC, HCT, Neutrophils ) P>0.05 in workers,compared to healthy control.
Correlation of TNF 308 Polymorphisms and Susceptibility to Respiratory Disease Shaimaa H. Al -Dulaimi; Adel M. Rabee
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16639

Abstract

l Both genotypic and allelic frequency of rs1800629 show in significant difference between concrete laborers and healthy controls. Nevertheless the frequency of A allele was insignificantly increase in laborers (20%) than in controls (14%) (P = 0.077; OR = 1.61; 95% CI = 0.72 to 3.58). After analyzing the relationship between TNFaserum levels of laborers and genotype of TNF-a-308G/A, we detected the laborers that carrying the GA and AA genotypes had significantly higher levels of TNFacompared to GG genotype carriers of rs1800629 ( P< 0.01). Consequently, our information proposed that TNF-a-308G/A variation was linked to risk of respiratory disease in concrete laborers. Moreover, we also identified TNF-a-308 A allele was the risk factor for concrete laborers in Iraqi population.
Co-Authors Esraa H. mohammed Shaimaa H. Al -Dulaimi