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All Journal Indian Journal of Forensic Medicine & Toxicology
Thikra Majid Muhammed AL-Obaidy
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Public Health

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Studying of Some Physiological Parameters in Patients with Inflammatory Bowel Disease ( IBD ) in Al-Anbar Province Thikra Majid Muhammed AL-Obaidy; Hasan Ali Mutar; Thaer Abdulqader Salih
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17544

Abstract

This study was carried out to determine some hematological, parameters in patients with IBD. the total number were 100 blood samples, 60 samples from patients with IBD (cases), while the remaining 40 samples from persons without IBD (control), Ages ranged from 15 to 60 years. who attended general teaching hospital in Ramadi city in Al-Anbar governorate. a comparison in hematological parameters was carried between the two groups with each other showed that there was significant difference between patients and control with (p<0.05). and the means levels for hemoglobin HB (10.09 g/dl), (13.18 g/dl) \ there was significant difference between patients and control with (p<0.05). and the means levels for red blood cells RBC (3.194 X 106 c/ mm3), (5.291X 106 c/ mm3) \ there was significant difference between patients and control with (p<0.05). and the means levels for white blood cells WBC (12.39X 103 c/ mm3), (7.300X 103 c/ mm3) there was significant difference between patients and control with (p<0.05). and the means levels for \platelet (561.2X 103 c/ mm3), (258.4X 103 c/ mm3).
Interlukine-17 Polymorphism in Patients with Inflammatory Bowel Disease ( IBD ) in Al-Anbar Province Thikra Majid Muhammed AL-Obaidy; Hasan Ali Mutar; Thaer Abdul Qader Saleh
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14840

Abstract

Tetra amplification refractory mutation system polymerase chain reaction technique (tetra ARMS PCR)ARMS-PCR method was used to genotyping of IL-17A and IL-17F , The impact of IL-17A and IL-17Fgenotypes on the production of interleukins in IBD patients and control groups were determined andInterleukins gene polymorphisms role in IBD infection. significant deference at (p ? 0.05 ) for each rs763780in IL-17 F in patients especially Genotype TT,TC,CC were 31 (51.67%),19 (31.67%),10 (16.67%) \ andrs2275913 in IL-17 A in patients especially Genotype GG,GA,AA were 18 (30%),23 (38.33%),19 (31.67%).As well as genotyping of rs763780 in IL-17 F showed significant increase at a significant level of P?0.05in both TC and CC genotypes in the cases samples compared with the control samples. the odds ratio was2.8894 and 22.3333 for TC and CC genotypes respectively at confidence interval up to 7.8 and 397 forboth genotypes. T allele are more frequent in both cases and control and it have odds ratio as 5.021 Andgenotyping of rs2275913 in IL-17 A showed significant increase at a significant level of P?0.01 for the AAgenotyping in the cases samples compared with the control samples, while the GA genotyping did not showany significant differences, ), the odds ratio for GA genotypes was 2.3590 at confidence interval up to 5.8,while it was 8.4444 at confidence interval up to 32.9 for AA genotypes. G allele are more frequent in bothcases and control and it have odds ratio as 3.319 at confidence interval up to 6
Co-Authors Hasan Ali Mutar Thaer Abdul Qader Saleh Thaer Abdulqader Salih