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All Journal Jurnal Novem Medika Farmasi Jurnal Sains dan Kesehatan
Hashary, A. Rufaidah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Pengaruh Pemberian Ekstrak Etanol Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Terhadap Kolesterol Mencit (mus musculus): EFFECT OF ETHANOL EXTRACT OF FRAGRANT PANDAN LEAVES (Pandanus amaryllifolius Roxb) ON CHOLESTEROL MICE (Mus musculus) Hashary, A. rufaidah
Jurnal Novem Medika Farmasi Vol. 1 No. 1: Volume 1 Issue 1
Publisher : Program Studi Farmasi, Universitas Islam Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59638/junomefar.v1i1.589

Abstract

Pandan Wangi leaves (Pandanus amaryllifolius Roxb) contain flavonoid chemicals found in fragrant pandan leaves which have antimicrobial, anticancer, antidiabetic, and lower cholesterol levels. The purpose of this study was to determine the effect of fragrant pandan leaf extract (Pandanus amaryllifolius Roxb) in lowering cholesterol in mice (Mus musculus) and to determine what dose of fragrant pandan leaf extract could lower cholesterol well in mice. The research method used is an experimental method using a maceration extraction process. This study used 15 mice (Mus musculus), then given fragrant pandan leaf extract (Pandanus amaryllifolius Roxb) with dosage variations of 40 mg/kgBW, 80 mg/kgBW, 160 mg/kgBW, negative control (Na.CMC), and a positive control (Simvastatin) previously induced by Alloxan. Cholesterol level examination was carried out twice, namely after Alloxan was induced and after being treated using a Nesco GCU measuring instrument. The result of this research is that pandan fragrant leaf extract (Pandanus amaryllifolius Roxb) can reduce cholesterol levels in the blood of mice (Mus musculus) where a dose concentration of 80 mg/kgBW shows the best dose in lowering cholesterol levels.
Identifikasi Drug Related Promblems (DRPs) Kategori Reaksi Obat Merugikan pada Pasien Penderita Hipertensi di Puskesmas X, Kabupaten Pangkep, Sulawesi Selatan: Identification of Drug Related Problems (DRPs) Category of Adverse Drug Reactions in Patients with Hypertension at X Health Center, Pangkep Regency, South Sulawesi Yunus, Arifuddin; Hashary, A. Rufaidah; Fajriani, Asruri
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2290

Abstract

Hypertension is a disease of increased systolic (>140 mmHg) and diastolic (>90 mmHg) blood pressure and is influenced by age, gender, genetics, diet, smoking and stress. Drug Related Problems (DRPs) are unexpected events in the therapeutic process and affect treatment, therefore the identification of DRPs can improve the effectiveness of treatment. This study aims to determine the incidence of DRPs in the category of adverse drug reactions in hypertensive patients at the X Health Center, Pangkep Regency. This study is a non-experimental study and the data were taken retrospectively. The population in this study were all hypertension patients from August to October 2022. Samples were taken by purposive sampling method according to the inclusion criteria. From this study, 63 patients (80.76%) had potential drug interactions out of 78 patients. Keywords:          Hypertension, Drug Related Problems (DRPs), Drug Interactions   Abstrak Hipertensi adalah penyakit peningkatan tekanan darah sistolik (>140 mmHg) dan diastolik (> 90 mmHg) dan dipengaruhi oleh faktor usia, jenis kelamin, genetika, pola makan, merokok dan stress. Drug Related Problems (DRPs) adalah kejadian tidak terduga pada proses terapi dan mempengaruhi pengobatan oleh karena itu identifikasi DRPs dapat meningkatkan efektivitas pengobatan. Penelitian ini bertujuan mengetahui kejadian DRPs kategori reaksi obat merugikan pada pasien hipertensi di Puskesmas X Kabupaten Pangkep. Penelitian ini merupakan penelitian noneksperimental dan data diambil secara retrospektif. Populasi dalam penelitian ini adalah semua pasien hipertensi bulan Agustus – Oktober 2022. Sampel diambil dengan metode purposif sampling sesuai kriteria inklusi. Dari penelitian ini diperoleh hasil 63 pasien (80,76%) terdapat potensi interaksi obat dari 78 pasien. Kata Kunci:         Hipertensi, Drug Related Problems (DRPs), Interaksi Obat
Co-Authors Fajriani, Asruri Yunus, Arifuddin