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All Journal Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Lucia Dwi Antika
Pusat Biomedis dan Teknologi Dasar Kesehatan, Jl. Percetakan Negara No. 29 Jakarta, Indonesia
Computer Science & IT Engineering Medicine & Pharmacology Social Sciences Other

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Conversion Eugenol to Vanillin: Evaluation of Antimicrobial Activity Triana, Desita; Tafdila, Muhammad Akbar; Antika, Lucia Dwi; Ernawati, Teni
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1431

Abstract

Indonesia is known as one of the largest clove producing countries in the world. About 75-90% main component of the clove oil is eugenol. Eugenol can be used as an analgesic, local anaesthetic, and also recognized as antimicrobial. Eugenol is known as starting material to produce synthetic vanillin. Vanillin is a compound that can be isolated from vanilla (Vanilla p lanifolia) or chemically synthesis. Vanillin is widely used for flavouring, fragrance, and also as a precursor of drugs in the pharmaceutical industry. Conversion eugenol to vanillin through several phases including isomerization, acetylation, oxidation, and hydrolysis. From each phase, it produces intermediate products, there are isoeugenol, isoeugenol acetate, and vanillin acetate, and also produce by-product vanillic acid. This present study aims to evaluate the results from the conversion of eugenol to vanillin for its antimicrobial activity against pathogenic bacteria E. coli and S. aureus. The result showed that eugenol, isoeugenol, vanillin acetate, vanillin and vanillic acid had antimicrobial activity. Isoeugenol which is the result of isomerization of eugenol is known to possess the best antimicrobial activity.
Co-Authors Tafdila, Muhammad Akbar Teni Ernawati Triana, Desita