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All Journal PRISMA FISIKA Jurnal Farmasi Indonesia Journal of Character and Environment
Astuti, Ayu Dwi
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Earth & Planetary Sciences Environmental Science Medicine & Pharmacology Physics Social Sciences Other

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Studi Sensitivitas Aliran Dalam Kanal Terbuka Menggunakan Pendekatan Komputasi Dinamika Fluida Model Turbulen K-Epsilon Astuti, Ayu Dwi; Putra, Yoga Satria; Kushadiwijayanto, Arie Antasari
PRISMA FISIKA Vol 9, No 2 (2021)
Publisher : Jurusan Fisika, Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/pf.v9i2.49488

Abstract

Penelitian ini dilakukan untuk menganalisis secara numerik sensitivitas aliran air dalam kanal terbuka menggunakan pendekatan komputasi dinamika fluida dengan bantuan perangkat lunak open source OpenFOAM yang menerapkan model turbulen RANS K-Epsilon. Simulasi aliran air dibangun dengan mengikuti tahapan eksperimen yang telah dilakukan oleh Coleman (1986). Simulasi aliran air berhasil dibangun yang ditunjukkan dengan pola grafik profil kecepatan aliran air yang mendekati data acuan eksperimen Coleman (1986) dan persamaan analitik Logarithmic Law pada ukuran grid irreguler Δx = 0,004 dan Δy = 0,01 m dan nilai k = 0,003. Nilai koefisien korelasi dan error yang didapat masing-masing adalah 0,996 dan 1,01 %. Berdasarkan hasil yang telah diperoleh, disimpulkan bahwa aliran air dalam sebuah kanal terbuka dapat disimulasikan menggunakan pendekatan komputasi dinamika fluida yang menerapkan model turbulen RANS K-Epsilon. Profil distribusi kecepatan air yang dihasilkan dalam simulasi ini telah menunjukkan kesamaan fisis dengan konsep mekanika fluia, yaitu kecepatan di dasar lebih rendah dibandingkan kecapatan di permukaan.Kata kunci: Aliran kanal terbuka, RANS K-Epsilon, OpenFOAM, Komputasi dinamika fluida
Behavior of coastal communities in dealing with microplastic pollution in salt ponds in Cirebon Regency Astuti, Ayu Dwi; Frimawaty, Evi; Dwiyitno
Journal of Character and Environment Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/jocae.v2i1.2024.780

Abstract

Background: Cirebon Regency, as one of the national salt-producing centers located on the coast of the North Coast of Java is vulnerable to plastic waste pollution originating from rivers and marine debris that washes up on the beach. The purpose of this study was to analyze an assessment of the correlation between aspects of knowledge and attitudes towards the behavior of coastal communities in domestic plastic waste was also carried out to be used as a basis for preparing strategies for managing domestic plastic waste in coastal communities. Methods: The research method used is a combination of quantitative and qualitative methods consisting of a shoreline survey methodology, river waste abundance, laboratory analysis, statistical analysis, questionnaires, semi-structured interviews, and descriptive analysis. Findings: Pearson's correlation analysis showed that there was a strong (r = 0.664) and significant (0.000) positive relationship between aspects of knowledge and behavior, then aspects of attitude and behavior had a very weak positive relationship (r = 0.183) and significant (0.028). Conclusion: The community has not been pro-environmental due to the uneven distribution of available cleaning facilities. The conclusion of this study is that education, community empowerment, collaboration between village and local officials, and additional cleaning facilities are needed to reduce the problem of domestic plastic waste. Novelty/Originality of this Study: The originality of this study lies in its examination of microplastic contamination in salt ponds, directly assessing the sources of contamination from raw materials and domestic waste in Cirebon Regency, a primary salt production area in Indonesia. This focus on the direct assessment of microplastic abundance in production units, rather than commercial products, provides novel insights into the impacts of plastic pollution on food safety and local salt quality.
Potensi Penghambatan Enzim Αlfa-Glukosidase dan Tes Toleransi Glukosa Oral (TTGO) Ektrak Daun Dadap Serep (Erythrina subumbrans (Hassk) Merr.): Susilawati, Elis; Astuti, Ayu Dwi; Sulaeman, Agus
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (567.773 KB) | DOI: 10.35617/jfionline.v15i1.135

Abstract

Abstract: Spare dadap plants contain flavonoids that can potentially lower glucose levels in the blood and reduce glucose absorption in the intestine. The purpose of the study was to determine the inhibitory activity of the α-glucosidase enzyme and the effect of giving Spare Dadap Leaf Ethanol Extract (EEDDS) on blood glucose levels of male white Wistar rats and its effective dose. The research method used the in vitro method with inhibition of α-glucosidase enzyme and the in vivo method Glucose Tolerance Test (TTGO) with amylum manihot induction using 25 rats divided into 5 groups with EEDDS doses of 100, 200, and 400 mg / kg BB, then measured blood glucose levels for 120 minutes. The results of the EEDDS α-glucosidase enzyme inhibition study showed the best % inhibition value of 41.81% at 100 ppm and the lowest % inhibition value at 10 ppm, which was 13.33% with an IC50 value of 146.30 ppm, which was included in the weak category in inhibiting α-glucosidase. The results of TTGO research induced amylum manihot, EEDDS 400 mg / KgBW have a significant effect on reducing blood glucose levels in the T60 to T120 range. The conclusion in this study is that spare dadap leaf ethanol extract has potential as an antihyperglycemic both in vitro and in vivo.
Co-Authors Agus Sulaeman Dwiyitno Evi Frimawaty Kushadiwijayanto, Arie Antasari Susilawati, Elis Yoga Satria Putra