Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana
I Wayan Ari Sumardika
Unknown Affiliation
Health Professions Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
TREATMENT OF DEPRESSION IN ELDERLY PATIENTS WITH CARDIOVASCULAR DISEASE I Wayan Ari Sumardika; Ni Ketut Sri Diniari
E-Jurnal Medika Udayana vol 2 no5(2013):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.258 KB)

Abstract

Cardiovascular disease and depression are two of the most common health problem that affect millions of people worldwide. Studies have shown that depression is a significant risk factor for newly diagnosed heart disease and that it increases morbidity and mortality in established heart disease. Many hypothesized and studied mechanisms have linked depression and heart disease, including serotonergic pathway and platelet dysfunction, inflammation, autonomic nervous system and hypothalamic-pituitary-adrenal axis imbalance, and psychosocial factors. The morbidity and mortality of cardiovascular disease is still associated with the treatment of depression. Understanding the impact and mechanisms behind the association of depression and heart disease may allow for the development of treatments aimed at reducing the bad outcomes that caused by these comorbid illnesses.
MANAGEMENT OF BREAST CANCER WITH BRCA GENE MUTATION I Wayan Ari Sumardika; I Wayan Sudarsa
E-Jurnal Medika Udayana vol 2 no 9 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.594 KB)

Abstract

The management of individual who has a genetic predisposition for breast cancer requires careful planning. It is estimated that 5-10% of breast cancer in Western countries is a hereditary breast cancer and 80-90% of them is the result of BRCA1 and BRCA2 genes mutations. The individual with BRCA1 and BRCA2 gene mutations have a high risk for experiencing breast cancer and other types of cancer, especially ovarian cancer. Although there are some differences, management of patients with hereditary breast cancer in principle is equal to management of non-hereditary breast cancer. Contra lateral mastectomy surgery and/or oophorectomy may be considered as initial therapy. The uses of breast conserving surgery in patients with BRCA-positive status are still controversial because of the risk of recurrence on ipsilateral breast, so did the use of ionization radiation modalities. Post surgery follow up is an important aspect in the management of patients with mutations of these genes in which follow up aims to find local recurrence, secondary breast cancer, contra lateral breast cancer as early as possible
Co-Authors I W. Sudarsa Ni Ketut Sri Diniari