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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Nasution, Fakhri Amin
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pituitary Macroadenoma with Apoplexy in an Adult: A Case Report Nasution, Fakhri Amin; Sazli, Brama Ihsan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 4 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (857.679 KB) | DOI: 10.32734/jetromi.v2i4.4909

Abstract

Abstract: Pituitary adenomas are the most common type and benign tumours arising from hormone expressing cells in the anterior pituitary gland. They account for 10% to 15% of all intracranial masses. Pituitary adenomas present clinically in three ways: syndromes of hormone hypersecretion or deficiency; neurologic manifestations from mass effect of an expanding gland; or an incidental finding on imaging done for an unrelated issue. A 49-years old man, was reffered to the hospital with symptoms of chronic headache and blurred vision. General physical examination revealed no abnormalities. History of previous illness and medication were unremarkable. MRI brain showed hyperintense lesion in suprasellar/selllar area. Hormone assay reciprocally revealed hypocortisolism and hyperprolactinemia. Abstrak: Adenoma hipofisis merupakan tumor jinak tersering dari sel penghasil hormon di kelenjar hipofisis anterior, berkisar 10%-15% dari seluruh massa intrakranial. Adenoma hipofisis secara klinis bermanifestasi dalam tiga cara: sindrom hipersekresi atau defisiensi hormon; manifestasi neurologis dari efek massa yang membesar; atau temuan secara tidak sengaja pada modalitas pencitraan. Seorang laki-laki berumur 49 tahun dirujuk ke rumah sakit dengan kkeluhan sakit kepala kronik dan pandangan kabur. Pemeriksaan fisik secara umum dalam batas normal. Riwayat penyakit sebelumnya atau pengobatan juga tidak spesifik. MRI otak menunjukkan lesi hiperintens pada area suprasellar/sellar. Temuan pemeriksaan hormon juga sejalan menunjukkan hipokortisolisme dan hiperprolaktinemia.
Correlation between Erythropoietin Resistance Index and Mortality in Regular Hemodialysis Patients at Haji Adam Malik General Hospital Medan Nasution, Fakhri Amin; Nasution, Alwi Thamrin; Nasution, Feldy G
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 2 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i2.12550

Abstract

Introduction: One of the functions of the kidneys is the production of erythropoietin, a signaling molecule that stimulates the production of red blood cells, in response to reduced oxygen levels in the blood. In chronic kidney disease, there is a disturbance in the production of erythropoietin. Several previous studies have linked the index of erythropoietin resistance to mortality in patients with chronic kidney disease. The study aimed to correlate between erythropoietin resistance index (ERI) and Mortality in regular hemodialysis patients. Method: Observational analytic study with a cross-sectional method to assess the relationship between ERI and mortality in all regular hemodialysis patients at H Adam Malik Medan. The ERI was used to evaluate erythropoietin EPO by comparing the dose of EPO to the hemoglobin level. The data were tested statistically with the Chi-Square method. Results: The average study subjects suffered from anemia with Hb levels of 8.21 g/dL, serum iron levels of 63.22 mcg/dL, and increased total iron-binding capacity (TIBC) levels with an average value of 190.2 mcg/dL, low ferritin levels of 195.59 mcg/L and serum transferrin (TSAT) 19.2%, and of 2.94 g/dL. Albumin levels, transferrin saturation, and ERI were associated with the mortality rate of patients undergoing regular hemodialysis (p=0.021; p=0.011; p=0.012). Conclusion: There is a relationship between the index of erythropoietin resistance and the mortality rate of patients undergoing regular hemodialysis
Co-Authors Brama Ihsan Sazli Nasution, Alwi Thamrin Nasution, Feldy G