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All Journal Archives of The Medicine and Case Reports Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Dian Primadia Putri
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Pituitary Macroadenoma Manifesting As Acromegaly: A Case Report Dian Primadia Putri; Sazli, Brama Ihsan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (558.432 KB) | DOI: 10.32734/jetromi.v3i1.5482

Abstract

Background: Acromegaly is an uncommon clinical disorder driven by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Over 99% of patients with acromegaly harbor a GH emitting pituitary adenoma. Pituitary tumors represent about 15% of essential intracranial neoplasms. Case presentation: A 38 years old woman, was referred to the H. Adam Malik central public hospital on December 15th, 2020, with chief complaints of enlarged fingers and toes. The patient complained that the patient's fingers and toes were getting bigger in the past 2 years. The brain MRI was performed showed intrasella spherical intensity lesions measuring ± 2.3x1.5x2 cm with the impression of macroadenoma. The patient later diagnosed with acromegaly due to pituitary macroadenoma. Therefore the patient was treated with administration of sandostatin injection, novorapid 6-6-6 IU SC, then 0-0-12 IU SC, 3x1 salt capsules. The patient is also consulted to the neurosurgery department for surgical management plans and a consulted to the Ophthalmology Department. Conclusion: We report an instance of acromegaly suspected because of pituitary macroadenoma in a patient with unmistakable clinical highlights, with comprehensive management.
Impact of COVID-19 on Acute Coronary Syndrome: An Examination of Mortality and Demographic Factors Dian Primadia Putri
Archives of The Medicine and Case Reports Vol. 6 No. 1 (2025): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v6i1.672

Abstract

The COVID-19 pandemic has significantly impacted cardiovascular health, with acute coronary syndrome (ACS) emerging as a major concern. This study investigates the relationship between demographic characteristics, mortality rates, and the incidence of ACS in COVID-19 patients. A retrospective study was conducted on a cohort of 68 patients diagnosed with both COVID-19 and ACS, admitted to a hospital in Medan between August 2020 and August 2021. Demographic data, COVID-19 severity, electrocardiogram (ECG) findings, and comorbid conditions were analyzed for their association with mortality. The mean age of the study participants was 58.2 years, with a male predominance (82.9%). The majority of patients experienced severe COVID-19 (62.9%), and the most common ECG finding was ST-elevation (62.9%). Hypertension was the most prevalent comorbidity (52.9%). Mortality was significantly associated with male gender (p=0.01) but not with COVID-19 severity, ECG findings, or comorbidities. In conclusion, male gender was identified as an independent predictor of mortality in COVID-19 patients with ACS. Further research is needed to elucidate the complex interplay of demographic factors, COVID-19, and ACS outcomes.
Co-Authors Brama Ihsan Sazli