Khalid M. Dakhel
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The Role of Oxidative Stress and Vitamin D in Aborted Women with Cytomegalovirus Raid M. H. Al-Salih; Khalid M. Dakhel; Batool A. Hussein
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17884

Abstract

Abortion is one of the commonest reasons for acute presentation to gynecologists, recurrent spontaneousabortion due to maternal infections transmissible in uterus at various stage of gestation can be causedby a wide array of organisms including cytomegalovirus. This study included (25) aborted women, (25)non- aborted women with cytomegalovirus seropositive test as a patients groups and (25) non- abortedwomen with cytomegalovirus seronegative test as a control group. The study was designed to evaluate theconcentration of malondialdehyde (MDA) as an oxidative stress marker, the concentration of ceruloplasmin(Cp) and transferrin (Tf) as an antioxidant marker and total vitamin D in cytomegalovirus infected womenand investigate the relation between oxidative stress and total vitamin D. The results show a significantdecrease in levels of serum MDA in aborted group with CMV in comparison to non-*-aborted and controlgroups (p> 0.05), serum ceruloplasmin and transferrin significantly decrease in aborted group in contrast tonon-aborted and control groups (p > 0.05) and total vitamin D was decreased in all study groups but therewas a significant difference between studied groups (p > 0.05). The results of this study show disorder inlevels of (MDA, Cp, Tf and VD) aborted group with cytomegalovirus.