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Rahmiati -
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Analisis Hubungan antara Ekspresi MMP-2 dengan Derajat Neoplasia Serviks pada Pap Smear Berbasis Cairan Marini Stephanie; Lisnawati -; Rahmiati -
Majalah Patologi Indonesia Vol 22 No 3 (2013): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

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Abstract

ABSTRAK Latar belakang MMP (matrix metalloproteinase) merupakan protease yang memiliki peran yang sangat penting pada proses invasi dan metastasis. Seiring dengan perkembangan pengetahuan mengenai akivitas MMP dan matriks esktraseluler, MMP dipikirkan juga ikut berkontribusi dalam lesi-lesi intraepitelial neoplasia serviks, salah satu diantaranya adalah MMP 2. MMP 2 merupakan salah satu anggota kelompok gelatinase yang sering dilaporkan kaitannya dengan progresifitas lesi kanker serviks, yang penelitiannya pada umumnya dilakukan pada jaringan. Tujuan penelitian ini adalah untuk mengetahui hubungan ekspresi MMP 2 dengan derajat neoplasia serviks yang dilakukan pada bahan sitologi berbasis cairan. Metode Penelitian ini dilakukan secara prospektif, menggunakan studi deskriptif analitik dengan disain potong lintang pada sediaan pap smear berbasis cairan yang telah didiagnosis sesuai dengan klasifikasi Bethesda 2001. Kasus dengan papsmear abnormal akan dilanjutkan dengan imunositokimia MMP 2. Hasil Terdapat hubungan bermakna antara ekspresi MMP 2 dengan derajat neoplasia serviks (p=0,001). Kesimpulan Ekspresi MMP 2 dapat ditemukan pada lesi atipikal, prekanker dan kanker invasif pada serviks. Tampak proporsi positifitas ekspresi MMP 2 lebih tinggi secara bermakna pada lesi derajat tinggi dibandingkan pada lesi derajat rendah. Kata kunci: MMP 2, derajat neoplasia serviks, pap smear berbasis cairan. ABSTRACT Background MMP (matrix metalloproteinase) ia a protease which have important role in the invasion and metastatic process. Resent study of the activity and extracellular matrix of MMP, especially MMP-2 is suspected contribute in the cervical intraepithelial neoplasia MMP-2 is one of the gelatinase group, that have been reported having correlation with cervical cancer progresivity. Many studies concerning the activity of MMP-2 in the tissues had been done. The aim of this study is to learn the relation of MMP-2 expression with cervical neoplasia grading using liquid base cervical cytology specimen. Methods This is a prospective study by cross sectional analysis using liquid base cytology slides, that was diagnosed according the Bethesda 2001 classification. All cases were reviewed and the abnormal cases were continued to immunocytochemistry staining using MMP-2 antibody. Results There were significantly association between MMP 2 and degree of neoplasia cervical lesion with p=0.001. Conclusion MMP 2 expression can occur in atypical, precancer and cancer lesions of the cervix. It was shown that high grade cervical lesions had higher proportion of MMP 2 positivity than low grade cervical lesions significantly. Key words : MMP 2, degree of neoplasia cervical lesions, liquid based cytology.
PENGARUH KEMAMPUAN TEHNOLOGI INFORMASI, KEMUDAHAN, RISIKO DAN FITUR LAYANAN TERHADAP MINAT NASABAH DALAM MENGGUNAKAN INTERNET BANKING (Studi Empiris Pada Nasabah Bank Rakyat Indonesia Di Kota Banjarmasin) Rusmanto -; Sri Mulyani; Rahmiati -
Dinamika Ekonomi - Jurnal Ekonomi dan Bisnis Vol 10 No 1 (2017): DINAMIKA EKONOMI Jurnal Ekonomi dan Bisnis Vol.10 No.1 Maret 2017
Publisher : SEKOLAH TINGGI ILMU EKONOMI NASIONAL (STIENAS) BANJARMASIN

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Abstract,This research aims to provide empirical evidence about the influence on the effect of technological capabilities, ease, risks, and service features to customers' interest in using internet banking at Bank BRI in Banjarmasin.The population in this study are all customers who use internet banking BRI BRI in the unit In Banjarmasin, Teluk Dalam unit, Pasar Lama unit and unit Belitung. Sampling technique used was quota sampling, in which the sample is chosen technique considering a relatively short research time and research objects consist of three units of BRI office. Additionally customers who use internet banking are visiting the office unit is also relatively small, so in this study the researchers gave the quota of each office unit of 20 people. The sample taken is 60 customers who use internet banking at BRI unit Teluk Dalam, in the pasar lama and the BRI BRI unit Belitung. Types and data sources of primary data obtained through a questionnaire distributed at bank customers as respondents, supplemented with secondary data obtained from various references. Multiple Linear Regression method used to test the hypothesis that has been proposed.The results of the study provide empirical evidence that the ability of information technology partially affect the interest of customers using internet banking, convenience partially affect the interest of customers using internet banking, risk is partially affect the interest of customers using internet banking, service features partially affect the interest of customers using internet banking. While simultaneously the ability of information technology affect the interest of customers using internet banking. The coefficient of determination adjusted R Square showed a value of 0.553 or 55.3%. Shows that the value of bank customers' interest in using internet banking can be explained by the ability of information technology, convenience, risk and service features of 55.3%. If adjusted R Square has a value> 0.5 s / d 1, is to have a strong influence.
PENGARUH KEMAMPUAN TEKNOLOGI INFORMASI, KEMUDAHAN, RISIKO DAN FITUR LAYANAN TERHADAP MINAT NASABAH DALAM MENGGUNAKAN INTERNET BANKING (Studi Empiris Pada Nasabah Bank Rakyat Indonesia Di Kota Banjarmasin) Ida Mentayani; Rusmanto Rusmanto; Rahmiati -
Dinamika Ekonomi - Jurnal Ekonomi dan Bisnis Vol 9 No 2 (2016): DINAMIKA EKONOMI Jurnal Ekonomi dan Bisnis Vol. 9 No. 2 September 2016
Publisher : SEKOLAH TINGGI ILMU EKONOMI NASIONAL (STIENAS) BANJARMASIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.982 KB)

Abstract

Abstract, This research aims to provide empirical evidence about the influence on the effect of technological capabilities, ease, risks, and service features to customers' interest in using internet banking at Bank BRI in Banjarmasin. The population in this research are all customers who use internet banking BRI BRI in the unit In Banjarmasin, Teluk Dalam unit, Pasar Lama unit and unit Belitung. Sampling technique used was quota sampling, in which the sample is chosen technique considering a relatively short research time and research objects consist of three units of BRI office. Additionally customers who use internet banking are visiting the office unit is also relatively small, so in this study the researchers gave the quota of each office unit of 20 people. The sample taken is 60 customers who use internet banking at BRI unit Teluk Dalam, in the pasar lama and the BRI BRI unit Belitung. Types and data sources of primary data obtained through a questionnaire distributed at bank customers as respondents, supplemented with secondary data obtained from various references. Multiple Linear Regression method used to test the hypothesis that has been proposed. The results of the research provide empirical evidence that the ability of information technology partially affect the interest of customers using internet banking, convenience partially affect the interest of customers using internet banking, risk is partially affect the interest of customers using internet banking, service features partially affect the interest of customers using internet banking. While simultaneously the ability of information technology affect the interest of customers using internet banking. The coefficient of determination adjusted R Square showed a value of 0.553 or 55.3%. Shows that the value of bank customers' interest in using internet banking can be explained by the ability of information technology, convenience, risk and service features of 55.3%. If adjusted R Square has a value> 0.5 s / d 1, is to have a strong influence.
Pengaruh Karakteristik Individu dan Karakteristik Sistem terhadap Niat untuk Menggunakan Teknologi Internet (Studi pada Dosen Universitas Negeri Padang) Rahmiati -
Jurnal Kajian Manajemen Bisnis Vol 1, No 1 (2012): Jurnal Kajian Manajemen Bisnis
Publisher : Jurusan Manajemen Fakultas Ekonomi Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (125.143 KB) | DOI: 10.24036/jkmb.477200

Abstract

The objective of this research was to investigates the effect of a set of individual characteristics (i.e., computer self efficacy, knowledge of search domain, and Internet experience) and system characteristics (i.e., complexity, relevance, and relative advantage) on intention to use Internet by using the Technology Acceptance Model (TAM) as a basic theory. Questionnaire survey method was used to collect primary data. Statistical analysis methods and Partial Least Square were used to data analyse.  Based on a sample of 181 lecturers in Universitas Negeri Padang, the survey result shows that the intention to use Internet influenced by system characteristics through perceived usefulness. Specifically, lecturers largely anchoring their acceptance decisions in the usefulness of the technology rather than in its ease of use. When making decisions to accept a technology, lecturers expressed considerable concerns about the relevance and the relative advantage of the technology on their activities. While individual characteristic variables i.e. computer self efficacy and Internet experience as like as system characteristic variable that is complexity are important determinants of  perceived ease of use, they do not affect the lecturer’s intention to use Internet.
Co-Authors I Gusti Agung Komang Diafari Djuni Hartawan Ida Mentayani Lisnawati - Marini Stephanie Rusmanto - Rusmanto Rusmanto