<![CDATA[Rheumatoid arthritis (RA) is considered as an autoimmune disease which influences the joints. It usuallyresults in a warm, enlarged, and painful joints. Stiffness and Pain typically amplify once relaxation.Frequently, the hands and wrist are involved, with similar joints naturally involved on both sides of the body.The syndrome might additionally have an impact on the other parts of the body. Adenosine Deaminase is anenzyme (EC 3.5.4.4) used with the metabolism of purine. It is essential for the analysis of adenosine fromnutrition and the revenue of nucleic acids in soft tissue. Its chief purpose in humans is the immune systemgrowth and preservation. On the other hand, the complete physiological role of ADA is so far not known.This study carried out at Al-Kadima Teaching Hospital, during the period fr6-om September 2014 till theend of October 2015. Patients who have any other disorders conditions are excluded. Subjects acceptingtreatment with medications within 7-9 months. A total of 66 patients with Rheumatoid arthritis wereenrolled in this study: thirty-five of them were newly diagnosed to have Rheumatoid arthritis who receivesno therapy for Rheumatoid arthritis (group A); the remaining thirty-one patients were with Rheumatoidarthritis who receive by methotrexate 500 mg for 7-9 months as the (group B). Twenty-six healthy subjects,as controls(group C ). The results show a significant elevation in the ADA activity in group A and group B.The study concluded that the level of ADA was higher in Iraqi RA patients than in healthy control subjects]]>
