Bernadette Dian Novita
Department of Pharmacology and Therapy, Faculty of Medicine Widya Mandala Catholic University Surabaya

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Hyper-coagulation and The Used of Anticoagulant for Patient with COVID-19 Alyssa Claudia V. Gunawan; Bernadette Dian Novita
JURNAL WIDYA MEDIKA Vol. 6 No. 2 (2020): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v6i2.2787

Abstract

Coronavirus SARS-CoV-2 (COVID-19) infection has become a global infection with high mortality and morbidity rate. The pathophysiology of COVID-19 has not yet clear but associated with increasing proinflammatory cytokines and chemokines that leads to cytokine storm. Cytokine storm leads to increasing coagulation that defined by increasing D-dimer, Prothrombin Time (PT), and activated partial thromboplastin time (aPTT). The use of anticoagulant in patient with COVID-19 decrease the mortality rate and become one of the recommended therapy.