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AKTIVITAS FRAKSI NONPOLAR DARI EKSTRAK ETANOL AKAR DADANGKAK (Hydrolea spinosa L) TERHADAP PENURUNAN KADAR GLUKOSA DARAH TIKUS JANTAN YANG DIINDUKSI ALOKSAN Muhammad Zaini; Jhudi Bonosari Soediono; Vivi Shofia; Amalia Ajrina
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 1 No 2 (2019)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.897 KB) | DOI: 10.52674/jkikt.v1i2.7

Abstract

Akar Dadangkak (Hydrolea spinosa L) secara empiris digunakan oleh masyarakat Kalimantan Selatan sebagai obat antidiabetes. Penelitian ini bertujuan untuk mengetahui efek antidiabetes fraksi nonpolar dari ekstrak etanol akar dadangkak. Penelitian dimulai dengan ekstraksi akar dadangkak (250 gram) secara maserasi dengan etanol, diperoleh ekstrak etanol (16,62 g). Ekstrak etanol difraksinasi dengan n-Heksan dan Petroleum Eter. Uji antidiabetes menggunakan tikus wistar jantan 20 ekor yang dibagi menjadi 4 kelompok Perlakuan. Kelompok I diberi akuades 2 mL/200 g BB ; kelompok II diberi Glibenklamid 0,45 mg/kgBB ; Kelompok III diberi fraksi n-heksan 100 mg/kg BB dan kelompok IV diberi fraksi Petroleum eter 100 mg/kg BB. Sebelum diberi perlakuan, tikus diinduksi Aloksan dengan dosis 150 mg/kg BB secara intraperitoneal. Hari ke-4 setelah induksi, tikus diberi perlakuan kontrol dan fraksi-fraksi selama 7 hari secara peroral. Pengukuran kadar glukosa darah dilakukan pada hari ke-1, 4 dan 12 menggunakan Gluco-DR. Kadar glukosa darah diuji dengan SPSS taraf kepercayaan 95 %. Hasil Penelitian menunjukkan rata-rata penurunan glukosa darah oleh fraksi n-heksan adalah 189,8 ± 13,59 mg/dL dan fraksi petroleum eter adalah 437,6 ± 8,98 mg/dL. Fraksi n-heksan mampu menurunkan kadar glukosa darah tikus secara signifikan (sig<0.05) dibandingkan terhadap kelompok kontrol. Sedangkan pemberian fraksi Petroleum eter tidak menujukkan penurunan glukosa darah yang signifikan (sig>0.05).
POLA PERSEPAN ANTIBIOTIK PADA PASIEN PNEUMONIA DI POLI ANAK RSUD DR. H. M. ANSARI SALEH BANJARMASIN TAHUN 2017 Muhammad Zaini; Muliyani Muliyani; Jhudi Bonosari Soediono; Elisa Destiana
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Pneumonia was a respiratory infection. Pneumonia was most often caused by bacterial, viral or mycoplasmic infections. The choice of therapy for pneumonia sufferers was generally given antibiotics. The purpose of this study was to determine the pattern of antibiotic use of pneumonia in pediatric patients in outpatient hospitals of dr. H. M. Ansari Saleh. The study was descriptive, data collection was carried out retrospectively in pneumonia patients who met the inclusion criteria was 52 samples. Data was taken from January to December 2017 through medical records. The results showed that pneumonia patients suffered the most from men by 26 cases (50%) and women by 26 cases (50%), based on the age of the most aged 1 - 12 months as many as 25 patients (48.07%). The use of antibiotics based on the selection of the most widely used groups is the third generation cephalosporins as many as 42 patients (80.76%), penicillin group as many as 6 patients (11.53%), the second generation cephalosporins as many as 4 patients (7.69%). The type of antibiotic that was often used is Cefixime as many as 46 users (88.46%), Amoxicillin as many as 6 users (11.53%), Cefadroxyl as many as 4 users (7.69%).
EFEKTIFITAS KOMBINASI GREEN TEA EXTRACT DAN SENOBI BREATHING EXERCISE UNTUK MENURUNKAN PREVALENSI LEMAK TUBUH REMAJA PADA KONDISI AKUT Nafi'ah Nafi'ah; Mu’jizatillah Mu’jizatillah; Jhudi Bonosari Soediono
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.587

Abstract

In last decade there has been an increase prevalence of overweight adolescents. Various strategies and products have been evaluated in effort to prevent and treat overweight using Green Tea Extract (GTE) and Senobi Breathing Exercise (SBE). However, the effect of GTE and SBE on decreasing adolescent body fat percentage in acute conditions when combined are unknown. The method used quasi experimental with control group design. The research conducted in Gymnasium laboratory of the Politeknik Unggulan Kalimantan in March 2020. The samples used were aged 18-21 years with BMI 25-29.9. Determination of samples using Federer's formula: (t-1) (n-1) ?15 obtained 4 treatment groups with a sample size of each group are 10 people that divided into: (a) overweight GTE; (b) overweight SBE; (c) overweight GTE and SBE; (d) overweight control . Measurement percentage of body fat in acute conditions shortly after treatment utilize Body Fat Monitor Scale GEA Medical EF 981. Statistical Test using Krusskall Wallis , the results obtained were P> 0.05, which indicates that there was no significant effect of GTE and SBE to reduce prevalence of adolescent body fat in acute conditions. Further research is needed to find out the correct protocol.