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All Journal Indian Journal of Forensic Medicine & Toxicology
Ra’no B. Azizova1, Nargiza N. Abdullaeva2, Iqrorjon I. Usmonaliev3
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Neuroimmunological Characteristics of Idiopathic and Symptomatic Epilepsy in Accordance with the Clinical Course Ra’no B. Azizova1, Nargiza N. Abdullaeva2, Iqrorjon I. Usmonaliev3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12869

Abstract

The authors have scientifically determined an immunoreactivity enhancement, which one can indicate bya change in the level of neurotropic autoantibodies in relation to proteins and neurotransmitter receptors inepileptogenesis and the formation of aberrant plasticity among patients with symptomatic and idiopathicepilepsy. Epilepsy is a variant of autoimmune dysregulation, in which an increase in the content ofautoantibodies in relation to neuro-specific proteins and neurotransmitters causes the genesis, progressionand preservation of the pathological process in accordance with the etiological factor.A new impulse to study the problem of epilepsy immunopathogenesis should be the ideas of in the lastdecade about the function inseparable integration of the two main integrative body systems: the central andthe immune nervous systems2. On the basis of information about neuroimmune interaction, new scientificdisciplines — Neuroimmunology and neuroimmunopathology formed5.
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