<![CDATA[Background: One of the most predominant periodontal diseases is the dental biofilm induced gingivitis. : Forthe past 20 years, super-oxidized solutions have been shown to be powerful antimicrobials and disinfectantsvia oxidative damage. The taste is better than chlorhexidine and doesn’t stain the teeth. Microsafe®, a superoxidized solution for gingival care, offers a completely improved approach to treatment of gingivitis.Aim: To evaluate the efficacy of super oxidized water mouthwash by improving gingival health in dentalbiofilm induced gingivitis. .Materials and Methods: 45 adult male patients with generalized dental biofilm induced gingivitisparticipated in the double blinded randomized controlled parallel study divided into three groups, twomouthwashes and distilled water( negative control) used during seven days periods as adjunctive to regularmechanical oral hygiene(brushing and interdental aids cleaning), one group received super oxidized watermouthwash (Microsafe®) three times daily and the second group received 0.12% alcohol-free chlorhexidinemouthwash (Kin gingival®) twice daily and the third group received distilled water twice daily (negativecontrol).Results: According to the plaque index, highly significant improvement of all treatment groups was observedin the second visit one-week post treatment. Microsafe® (SOW) showed to have clinical outcomes closedto the effect of CHX (the positive control) than the negative control group (D.W group). According to theGI, there was a significant difference between the study groups in the2nd visit after treatment and CHX wasappeared to be most effective when compared to Microsafe®.According to BOP , all the treatment groups showed reduced BOP one-week between the 1st visit and the 2ndvisit ; although, CHX showed better outcomes (the mean difference was 14.258 ) when compared to D.Wand Microsafe® groups( the mean differences were 10.838, 9.9 respectively).Conclusion: There was a positive effect of topical application of Microsafe® mouthwash as adjunctiveto regular mechanical oral hygiene on gingival inflammation three times daily after one week. This wasimproved by clinical periodontal parameters (PlI , GI and BOP).]]>
